CEP290

Description		centrosomal protein 290
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Membrane Cytoplasmic Vesicle Photoreceptor Connecting Cilium Protein-containing Complex Centriolar Satellite Specific Granule Lumen Ciliary Transition Zone MKS Complex Ciliary Basal Body Cell Projection
	Molecular Function	Protein Binding Identical Protein Binding Microtubule Minus-end Binding
	Biological Process	Kidney Development Protein Transport Cell Projection Organization Hindbrain Development Otic Vesicle Formation Eye Photoreceptor Cell Development Camera-type Eye Development Positive Regulation Of DNA-templated Transcription Pronephros Development Cilium Assembly Regulation Of Establishment Of Protein Localization Positive Regulation Of Intracellular Protein Transport Ciliary Basal Body-plasma Membrane Docking Ciliary Transition Zone Assembly Non-motile Cilium Assembly
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane Neutrophil degranulation AURKA Activation by TPX2
Drugs
Diseases		Meckel syndrome (MKS); Meckel-Gruber syndrome Bardet-Biedl syndrome (BBS) Leber congenital amaurosis (LCR) Senior-Loken syndrome Joubert syndrome
GWAS		Clozapine-induced agranulocytosis ( 25187353) Mild influenza (H1N1) infection ( 26379185)
Interacting Genes		7 interacting genes: BBLN CC2D2A CREBBP KIAA1328 MAPK10 PICK1 TTC3
Entrez ID		80184
HPRD ID
Ensembl ID		ENSG00000198707
Uniprot IDs		A0A6Q8PGB1 A0A6Q8PGP6 J3KNF5 O15078 Q05BJ6
PDB IDs
Enriched GO Terms of Interacting Partners?
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