ESRP2 and CYB5B

		ESRP2	CYB5B
Description		epithelial splicing regulatory protein 2	cytochrome b5 type B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Ribonucleoprotein Complex	Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Membrane Membrane Intracellular Membrane-bounded Organelle Nitric-oxide Synthase Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding	Protein Binding Heme Binding Metal Ion Binding Nitrite Reductase (NO-forming) Activity
	Biological Process	Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Regulation Of RNA Splicing Epithelial Cell Proliferation Positive Regulation Of Epithelial Cell Proliferation Epithelial Tube Branching Involved In Lung Morphogenesis Branching Involved In Salivary Gland Morphogenesis	Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Response To Oxidative Stress
Pathways		FGFR2 alternative splicing	Sphingolipid de novo biosynthesis eNOS activation Phase I - Functionalization of compounds
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS		Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Blood osmolality (transformed sodium) ( 28360221) Blood pressure (smoking interaction) ( 25189868) Body mass index ( 26426971) Heel bone mineral density ( 30598549) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 29403010 30993211)
Interacting Genes		1 interacting genes: NUMBL	51 interacting genes: AHNAK2 APP AQP6 BIK BNIP3L BTNL9 CD33 CD79A CGRRF1 CLDN7 CLN8 CPLX4 CREB3 EBP ERGIC3 FAM209A FAM210B FKBP7 FNDC9 FRMD3 GJB5 GPR152 IGSF9 KCNK5 KIR2DL3 LMNA MARCHF8 MFF MUC1 NDUFAF2 PDZK1IP1 PHACTR3 PLPP4 REEP4 RETREG3 SDHAF4 SLC10A1 SLC10A6 SLC16A2 SLC35H1 SLC39A9 SLC60A2 SLC71A2 STOM STX1A SYT1 TMEM139 TMEM237 TMEM35A TMEM41A TMEM86B
Entrez ID		80004	80777
HPRD ID		07971	13106
Ensembl ID		ENSG00000103067	ENSG00000103018
Uniprot IDs		A0A0A1TE42 Q9H6T0	O43169
PDB IDs			3NER
Enriched GO Terms of Interacting Partners?			Membrane
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