SLC35E1 and MCOLN1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SLC35E1	MCOLN1
Gene Name		solute carrier family 35, member E1	mucolipin 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Cytoplasm Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane Endosome Membrane Integral Component Of Membrane Late Endosome Membrane Receptor Complex
	Molecular Function		Cation Channel Activity NAADP-sensitive Calcium-release Channel Activity
	Biological Process	Transport	Cation Transport Cellular Iron Ion Homeostasis Transferrin Transport Ion Transmembrane Transport Release Of Sequestered Calcium Ion Into Cytosol Transmembrane Transport Calcium Ion Transmembrane Transport
Pathways			Ion channel transport Iron uptake and transport TRP channels Stimuli-sensing channels Transferrin endocytosis and recycling
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: ABCF3 FXYD6 LAMA3 MCOLN1	2 interactors: SLC35E1 TRIM27
Entrez ID		79939	57192
HPRD ID		15373	05582
Ensembl ID		ENSG00000127526	ENSG00000090674
Uniprot IDs		Q96K37	Q9GZU1
PDB IDs
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Calcium Ion Import Interferon-gamma Secretion Negative Regulation Of Viral Release From Host Cell Interferon-gamma Production Negative Regulation Of Interleukin-2 Production Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Regulation Of Calcium Ion Import Protein K63-linked Ubiquitination Cytokine Secretion Protein Trimerization Negative Regulation Of Cytokine Secretion Negative Regulation Of Adaptive Immune Response Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Negative Regulation Of Calcium Ion Transport Arp2/3 Complex-mediated Actin Nucleation Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Transmembrane Transport Actin Nucleation Retrograde Transport, Endosome To Golgi Regulation Of Viral Transcription Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Viral Process
Tagcloud ?			channel contraction defective disabilities dystrophic dystrophies dystrophin endosomal exocytosis facilitated fibers mdx ml1 ml4 mucolipidosis muscular normally null resealing sarcolemmal sensor skeletal trpml1 upmodulating vesicle vesicles vesicular wasting weakness
Tagcloud (Difference) ?			channel contraction defective disabilities dystrophic dystrophies dystrophin endosomal exocytosis facilitated fibers mdx ml1 ml4 mucolipidosis muscular normally null resealing sarcolemmal sensor skeletal trpml1 upmodulating vesicle vesicles vesicular wasting weakness
Tagcloud (Intersection) ?