MCOLN1 and SLC35E1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MCOLN1	SLC35E1
Gene Name		mucolipin 1	solute carrier family 35, member E1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane Endosome Membrane Integral Component Of Membrane Late Endosome Membrane Receptor Complex	Integral Component Of Membrane
	Molecular Function	Cation Channel Activity NAADP-sensitive Calcium-release Channel Activity
	Biological Process	Cation Transport Cellular Iron Ion Homeostasis Transferrin Transport Ion Transmembrane Transport Release Of Sequestered Calcium Ion Into Cytosol Transmembrane Transport Calcium Ion Transmembrane Transport	Transport
Pathways		Ion channel transport Iron uptake and transport TRP channels Stimuli-sensing channels Transferrin endocytosis and recycling
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: SLC35E1 TRIM27	4 interactors: ABCF3 FXYD6 LAMA3 MCOLN1
Entrez ID		57192	79939
HPRD ID		05582	15373
Ensembl ID		ENSG00000090674	ENSG00000127526
Uniprot IDs		Q9GZU1	Q96K37
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Calcium Ion Import Interferon-gamma Secretion Negative Regulation Of Viral Release From Host Cell Interferon-gamma Production Negative Regulation Of Interleukin-2 Production Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Regulation Of Calcium Ion Import Protein K63-linked Ubiquitination Cytokine Secretion Protein Trimerization Negative Regulation Of Cytokine Secretion Negative Regulation Of Adaptive Immune Response Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Negative Regulation Of Calcium Ion Transport Arp2/3 Complex-mediated Actin Nucleation Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Transmembrane Transport Actin Nucleation Retrograde Transport, Endosome To Golgi Regulation Of Viral Transcription Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Viral Process
Tagcloud ?		channel contraction defective disabilities dystrophic dystrophies dystrophin endosomal exocytosis facilitated fibers mdx ml1 ml4 mucolipidosis muscular normally null resealing sarcolemmal sensor skeletal trpml1 upmodulating vesicle vesicles vesicular wasting weakness
Tagcloud (Difference) ?		channel contraction defective disabilities dystrophic dystrophies dystrophin endosomal exocytosis facilitated fibers mdx ml1 ml4 mucolipidosis muscular normally null resealing sarcolemmal sensor skeletal trpml1 upmodulating vesicle vesicles vesicular wasting weakness
Tagcloud (Intersection) ?