MCOLN1

Description		mucolipin TRP cation channel 1
Image
GO Annotations	Cellular Component	Phagocytic Cup Nucleoplasm Lysosome Lysosomal Membrane Endosome Late Endosome Golgi Apparatus Plasma Membrane Endosome Membrane Membrane Cytoplasmic Vesicle Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Late Endosome Membrane Cell Projection Receptor Complex
	Molecular Function	Monoatomic Anion Channel Activity Monoatomic Cation Channel Activity Calcium Channel Activity Potassium Channel Activity Sodium Channel Activity Iron Ion Transmembrane Transporter Activity Protein Binding Lipid Binding Identical Protein Binding NAADP-sensitive Calcium-release Channel Activity Intracellularly Phosphatidylinositol-3,5-bisphosphate-gated Monatomic Cation Channel Activity Ligand-gated Calcium Channel Activity
	Biological Process	Adaptive Immune Response Immune System Process Monoatomic Ion Transport Monoatomic Cation Transport Calcium Ion Transport Lysosome Organization Calcium-mediated Signaling Transferrin Transport Monoatomic Ion Transmembrane Transport Iron Ion Transmembrane Transport Sodium Ion Transmembrane Transport Negative Regulation Of Innate Immune Response Release Of Sequestered Calcium Ion Into Cytosol Protein Homotetramerization Calcium Ion Transmembrane Transport Cellular Response To Calcium Ion Cellular Response To PH Potassium Ion Transmembrane Transport Phagosome Maturation Autophagosome Maturation Monoatomic Cation Transmembrane Transport Monoatomic Anion Transmembrane Transport Antibacterial Innate Immune Response Negative Regulation Of Protein Localization To Nucleus Positive Regulation Of Protein Localization To Nucleus Calcium Ion Export Positive Regulation Of Lysosome Organization
Pathways		TRP channels Transferrin endocytosis and recycling
Drugs
Diseases		Mucolipidosis IV
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Mean platelet volume ( 32888494) Opioid overdose severity score ( 31362332)
Interacting Genes		5 interacting genes: APPBP2 GPR35 SEC22A SLC35E1 TRIM27
Entrez ID		57192
HPRD ID		05582
Ensembl ID		ENSG00000090674
Uniprot IDs		Q9GZU1
PDB IDs		5TJA 5TJB 5TJC 5WJ5 5WJ9 6E7P 6E7Y 6E7Z 7MGL
Enriched GO Terms of Interacting Partners?
Tagcloud ?