MTERF1 and SYTL2

Number of citations of the paper that reports this interaction (PMID 20195357)
18

Data Source:
BioGRID (pull down)

		MTERF1	SYTL2
Gene Name		mitochondrial transcription termination factor 1	synaptotagmin-like 2
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Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Plasma Membrane Membrane Extrinsic Component Of Plasma Membrane Melanosome Exocytic Vesicle
	Molecular Function	Double-stranded DNA Binding Protein Binding Poly(A) RNA Binding	Phosphatidylserine Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Rab GTPase Binding Phosphatase Binding Neurexin Family Protein Binding
	Biological Process	DNA-templated Transcription, Termination Regulation Of Transcription, DNA-templated Transcription From Mitochondrial Promoter Termination Of Mitochondrial Transcription Organelle Organization Mitochondrion Organization Gene Expression DNA Geometric Change	Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Negative Regulation Of Phosphatase Activity Vesicle-mediated Transport Positive Regulation Of Mucus Secretion
Pathways		Organelle biogenesis and maintenance RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Transcription from mitochondrial promoters Transcriptional activation of mitochondrial biogenesis Mitochondrial transcription termination Mitochondrial biogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: DCTN1 DNAJC21 EXOC6B SET SYTL2	6 interactors: FBXO25 MTERF1 NRXN1 PPP1CA RAB27A RAB27B
Entrez ID		7978	54843
HPRD ID		08373	10260
Ensembl ID		ENSG00000127989	ENSG00000137501
Uniprot IDs		B4DPR9 Q99551	Q9HCH5
PDB IDs		3MVA 3MVB 3N6S 3N7Q	3BC1
Enriched GO Terms of Interacting Partners?		Vesicle Docking Involved In Exocytosis Vesicle Docking Membrane Docking Establishment Of Localization In Cell Cellular Localization	Multivesicular Body Sorting Pathway Vesicle Localization Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Cellular Pigmentation Rab Protein Signal Transduction Positive Regulation Of Exocytosis Vesicle Docking Involved In Exocytosis Organelle Localization Vesicle Docking Secretion By Cell Membrane Docking Positive Regulation Of Constitutive Secretory Pathway Protein Complex Assembly Involved In Synapse Maturation Termination Of Mitochondrial Transcription Gamma-aminobutyric Acid Receptor Clustering Complement-dependent Cytotoxicity Pigmentation Secretion Regulation Of Secretion Protein Secretion Multivesicular Body Organization Guanylate Kinase-associated Protein Clustering Neuroligin Clustering Cytotoxic T Cell Degranulation Regulation Of Exocytosis Gephyrin Clustering Synaptic Vesicle Clustering Exosomal Secretion Neuronal Signal Transduction Establishment Of Vesicle Localization N-methyl-D-aspartate Receptor Clustering Vocal Learning Ras Protein Signal Transduction Negative Regulation Of Filopodium Assembly Postsynaptic Membrane Assembly Natural Killer Cell Degranulation Regulation Of Cellular Localization Synapse Maturation Regulation Of Grooming Behavior Presynaptic Membrane Assembly Postsynaptic Density Protein 95 Clustering T Cell Mediated Cytotoxicity Regulation Of Glycogen Catabolic Process Receptor Localization To Synapse Presynaptic Membrane Organization Auditory Behavior Establishment Of Organelle Localization
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