SNIP1 and SH3D21

		SNIP1	SH3D21
Description		Smad nuclear interacting protein 1	SH3 domain containing 21
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2 SnRNP Cytosol U2-type Precatalytic Spliceosome
	Molecular Function	RNA Binding MRNA Binding Protein Binding Transcription Regulator Inhibitor Activity
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Regulation Of Gene Expression Regulatory NcRNA-mediated Gene Silencing MiRNA Processing Negative Regulation Of Canonical NF-kappaB Signal Transduction U2-type Prespliceosome Assembly	Actin Filament Organization Cell Migration
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Axial length ( 24144296) Eyebrow thickness ( 26926045)	Immature fraction of reticulocytes ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		47 interacting genes: CDK6 CREBBP DVL2 DVL3 EIF3C EP300 ESRRG FAF1 GMEB1 GYS1 HIPK1 HIPK3 KRTAP10-6 MAX MYC PHF19 PIAS1 PIAS2 PIAS3 PIAS4 POU2F1 PRPF3 PRPF40A RELA SETDB1 SF3B1 SMAD1 SMAD2 SMAD4 SON SP100 SPANXN2 SRPK2 SRRM4 STK3 TDG TNIP1 TOPORS TSPYL2 TTC14 UBE2I ZBTB9 ZCCHC10 ZCCHC7 ZMYM2 ZMYM5 ZNF451	1 interacting genes: YAP1
Entrez ID		79753	79729
HPRD ID		06999	08011
Ensembl ID		ENSG00000163877	ENSG00000214193
Uniprot IDs		B1AK66 Q8TAD8	A4FU49
PDB IDs		5Z56 5Z57 5Z58 6FF7 7ABG 7ABH 7ABI 7DVQ 8I0P 8I0R
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process PML Body Chromatin Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Nucleoplasm Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Primary Metabolic Process SUMO Transferase Activity Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Protein Sumoylation SUMO Ligase Activity Positive Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription Coregulator Activity Positive Regulation Of Transcription By RNA Polymerase II DNA Binding Positive Regulation Of Biosynthetic Process SMAD Protein Signal Transduction Positive Regulation Of MiRNA Transcription Negative Regulation Of Macromolecule Metabolic Process Nucleic Acid Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of MiRNA Metabolic Process Transcription Regulator Complex DNA-binding Transcription Factor Binding Nuclear Speck DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of Metabolic Process Regulation Of MiRNA Transcription DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Metabolic Process Regulation Of MiRNA Metabolic Process Nucleobase-containing Compound Metabolic Process	Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation ADP Catabolic Process Positive Regulation Of Heart Growth ADP Metabolic Process Branch Elongation Of An Epithelium Lateral Mesoderm Development Regulation Of Cardiac Muscle Cell Proliferation Nucleoside Diphosphate Catabolic Process Positive Regulation Of Notch Signaling Pathway Positive Regulation Of Cardiac Muscle Cell Proliferation Protein-containing Complex Organization Cellular Response To Gamma Radiation Ribonucleoside Diphosphate Catabolic Process Negative Regulation Of Gene Expression Intestinal Epithelial Cell Development Bud Elongation Involved In Lung Branching Glandular Epithelial Cell Differentiation Response To Progesterone Lung Epithelial Cell Differentiation Negative Regulation Of Fat Cell Differentiation Heart Process Regulation Of Keratinocyte Proliferation Regulation Of Nephron Tubule Epithelial Cell Differentiation TEAD-YAP Complex Hippo Signaling Notochord Development Negative Regulation Of Stem Cell Differentiation Glycolytic Process Through Fructose-6-phosphate Glucose Catabolic Process Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Female Germ Cell Nucleus Polarized Epithelial Cell Differentiation Trophectodermal Cell Differentiation Glycolytic Process Through Glucose-6-phosphate Negative Regulation Of Signal Transduction Cardiac Muscle Tissue Regeneration Positive Regulation Of Organ Growth Positive Regulation Of Stem Cell Population Maintenance Purine Ribonucleoside Diphosphate Catabolic Process Organ Growth Enterocyte Differentiation Paraxial Mesoderm Development Intestinal Epithelial Cell Differentiation Protein-containing Complex Assembly Lung Cell Differentiation Columnar/cuboidal Epithelial Cell Development Negative Regulation Of Epithelial Cell Apoptotic Process Response To Gamma Radiation Negative Regulation Of Cilium Assembly Regulation Of Epithelial Cell Apoptotic Process
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