SNIP1 and AKIRIN1

		SNIP1	AKIRIN1
Description		Smad nuclear interacting protein 1	akirin 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2 SnRNP Cytosol U2-type Precatalytic Spliceosome	Chromatin Nucleus Nucleoplasm Nuclear Membrane
	Molecular Function	RNA Binding MRNA Binding Protein Binding Transcription Regulator Inhibitor Activity	Transcription Coregulator Activity Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Regulation Of Gene Expression Regulatory NcRNA-mediated Gene Silencing MiRNA Processing Negative Regulation Of Canonical NF-kappaB Signal Transduction U2-type Prespliceosome Assembly	Positive Regulation Of Lamellipodium Assembly Positive Regulation Of Macrophage Chemotaxis Myoblast Migration Involved In Skeletal Muscle Regeneration Positive Regulation Of Myoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Skeletal Muscle Satellite Cell Proliferation Negative Regulation Of Satellite Cell Differentiation
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Axial length ( 24144296) Eyebrow thickness ( 26926045)	Beard thickness ( 26926045)
Interacting Genes		47 interacting genes: CDK6 CREBBP DVL2 DVL3 EIF3C EP300 ESRRG FAF1 GMEB1 GYS1 HIPK1 HIPK3 KRTAP10-6 MAX MYC PHF19 PIAS1 PIAS2 PIAS3 PIAS4 POU2F1 PRPF3 PRPF40A RELA SETDB1 SF3B1 SMAD1 SMAD2 SMAD4 SON SP100 SPANXN2 SRPK2 SRRM4 STK3 TDG TNIP1 TOPORS TSPYL2 TTC14 UBE2I ZBTB9 ZCCHC10 ZCCHC7 ZMYM2 ZMYM5 ZNF451	2 interacting genes: GOPC USP7
Entrez ID		79753	79647
HPRD ID		06999	07787
Ensembl ID		ENSG00000163877	ENSG00000174574
Uniprot IDs		B1AK66 Q8TAD8	Q9H9L7
PDB IDs		5Z56 5Z57 5Z58 6FF7 7ABG 7ABH 7ABI 7DVQ 8I0P 8I0R
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process PML Body Chromatin Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Nucleoplasm Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Primary Metabolic Process SUMO Transferase Activity Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Protein Sumoylation SUMO Ligase Activity Positive Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription Coregulator Activity Positive Regulation Of Transcription By RNA Polymerase II DNA Binding Positive Regulation Of Biosynthetic Process SMAD Protein Signal Transduction Positive Regulation Of MiRNA Transcription Negative Regulation Of Macromolecule Metabolic Process Nucleic Acid Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of MiRNA Metabolic Process Transcription Regulator Complex DNA-binding Transcription Factor Binding Nuclear Speck DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of Metabolic Process Regulation Of MiRNA Transcription DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Metabolic Process Regulation Of MiRNA Metabolic Process Nucleobase-containing Compound Metabolic Process	Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Anion Channel Activity Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Retrograde Transport, Endosome To Golgi Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Monoubiquitinated Protein Deubiquitination DNA Alkylation Repair Regulation Of Telomere Capping Transcription-coupled Nucleotide-excision Repair Negative Regulation Of Protein Localization To Cell Surface Regulation Of Monoatomic Anion Transport Golgi-associated Vesicle Membrane Apical Protein Localization Molecular Sequestering Activity Trans-Golgi Network Transport Vesicle K48-linked Deubiquitinase Activity Negative Regulation Of Gluconeogenesis
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