CLIP4 and SPDYA

		CLIP4	SPDYA
Description		CAP-Gly domain containing linker protein family member 4	speedy/RINGO cell cycle regulator family member A
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GO Annotations	Cellular Component	Nucleus Cell Cortex Microtubule Plus-end	Chromosome, Telomeric Region XY Body Nucleus Nuclear Envelope Nucleoplasm
	Molecular Function	Protein Binding Microtubule Plus-end Binding	Protein Binding Protein Kinase Binding Protein Kinase Activator Activity
	Biological Process	Cytoplasmic Microtubule Organization	G1/S Transition Of Mitotic Cell Cycle DNA Damage Response Male Meiotic Nuclear Division Spermatogenesis Positive Regulation Of Cell Population Proliferation Telomere Capping Positive Regulation Of Protein Kinase Activity Oogenesis Meiotic Attachment Of Telomere To Nuclear Envelope Establishment Of Protein Localization To Telomere
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)
Interacting Genes		37 interacting genes: APP CDK5RAP2 CLIP1 CMYA5 DCAF6 DES DST DYNC2LI1 GLP1R HSF2BP JAKMIP2 KIF1B KIFC3 LZTS2 MAGEA12 MAP7 MAP7D1 MEOX2 MYBPC1 MYH3 PDE4DIP PEG10 RPS13 RPS27L RUNX1 SIX2 SON TACC3 TAF1 TNNT1 TNNT3 TPM1 TRIM32 TRIP13 TTN TULP3 ZNF114	5 interacting genes: AQP1 CDK2 CDK5 CDKN1B FBXO7
Entrez ID		79745	245711
HPRD ID		08634	18095
Ensembl ID		ENSG00000115295	ENSG00000163806
Uniprot IDs		A0A8I5KXU9 A0A8I5QKP4 A0A8I5QKV0 A8K6D0 B7Z936 G3XAK3 Q8N3C7	A0A384MTT5 Q5MJ70
PDB IDs		2Z0W	5UQ1 5UQ2 5UQ3 7E34
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Sarcomere Organization Organelle Organization Microtubule-based Process Microtubule Cytoskeleton Organization Actomyosin Structure Organization Microtubule Skeletal Muscle Contraction Striated Muscle Contraction Microtubule Binding Muscle Filament Sliding Muscle Contraction Actin-myosin Filament Sliding Centrosome Actin Cytoskeleton Organization Cytoskeleton Microtubule Plus-end Microtubule Cytoskeleton Muscle System Process M Band Actin Filament-based Process Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Microtubule Polymerization Actin-mediated Cell Contraction Female Meiosis I Structural Constituent Of Muscle Troponin Complex Myofibril Male Meiotic Nuclear Division Regulation Of Supramolecular Fiber Organization Actin Filament-based Movement Contractile Muscle Fiber Tropomyosin Binding Regulation Of Microtubule Polymerization Cytoskeletal Protein Binding Regulation Of Microtubule Cytoskeleton Organization Transport Along Microtubule Meiotic Nuclear Division Female Meiotic Nuclear Division Axo-dendritic Transport Positive Regulation Of Cytoskeleton Organization Supramolecular Fiber Organization Retrograde Axonal Transport Microtubule Plus-end Binding Positive Regulation Of Protein Polymerization Cytoskeleton-dependent Intracellular Transport Myosin Filament Nuclear Division Regulation Of Cytoskeleton Organization Amyloid-beta Complex	Cellular Response To Nitric Oxide Cellular Response To Reactive Nitrogen Species Response To Nitric Oxide Potassium Ion Transport Negative Regulation Of Cell Cycle Regulation Of Cell Cycle Phase Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Metal Ion Transport Regulation Of Cell Cycle G1/S Phase Transition Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Mitotic Cell Cycle Cyclin Binding Monoatomic Cation Transport Sensory Perception Of Pain Regulation Of Cell Cycle Process Positive Regulation Of DNA Replication Cyclin-dependent Protein Kinase Holoenzyme Complex Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Monoatomic Ion Transport Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Cellular Senescence Negative Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Presynaptic Cytosolic Calcium Concentration Cyclin-dependent Protein Kinase Regulator Activity Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Regulation Of Cell Cycle Regulation Of Locomotion G1/S Transition Of Mitotic Cell Cycle Cell Cycle G1/S Phase Transition Sensory Perception Metanephric Glomerulus Vasculature Development Glycerol Transmembrane Transporter Activity Corticotropin Secretion Regulation Of Mitotic Cell Cycle Y Chromosome Positive Regulation Of Heterochromatin Formation Cyclin A1-CDK2 Complex Cyclin E2-CDK2 Complex Positive Regulation Of DNA-templated DNA Replication Initiation Acetylcholine Receptor Activator Activity Negative Regulation Of Developmental Growth Negative Regulation Of Cardiac Muscle Tissue Regeneration
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