SPDYA

Description		speedy/RINGO cell cycle regulator family member A
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GO Annotations	Cellular Component	Chromosome, Telomeric Region XY Body Nucleus Nuclear Envelope Nucleoplasm
	Molecular Function	Protein Binding Protein Kinase Binding Protein Kinase Activator Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle DNA Damage Response Male Meiotic Nuclear Division Spermatogenesis Positive Regulation Of Cell Population Proliferation Telomere Capping Positive Regulation Of Protein Kinase Activity Oogenesis Meiotic Attachment Of Telomere To Nuclear Envelope Establishment Of Protein Localization To Telomere
Pathways
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)
Novel Interacting Genes		2 novel interacting genes: CLIP4 DCAF7
Interacting Genes		5 interacting genes: AQP1 CDK2 CDK5 CDKN1B FBXO7
Entrez ID		245711
HPRD ID		18095
Ensembl ID		ENSG00000163806
Uniprot IDs		A0A384MTT5 Q5MJ70
PDB IDs		5UQ1 5UQ2 5UQ3 7E34
Enriched GO Terms of Interacting Partners?		Cellular Response To Nitric Oxide Cellular Response To Reactive Nitrogen Species Response To Nitric Oxide Potassium Ion Transport Negative Regulation Of Cell Cycle Regulation Of Cell Cycle Phase Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Metal Ion Transport Regulation Of Cell Cycle G1/S Phase Transition Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Mitotic Cell Cycle Cyclin Binding Monoatomic Cation Transport Sensory Perception Of Pain Regulation Of Cell Cycle Process Positive Regulation Of DNA Replication Cyclin-dependent Protein Kinase Holoenzyme Complex Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Monoatomic Ion Transport Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Cellular Senescence Negative Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Presynaptic Cytosolic Calcium Concentration Cyclin-dependent Protein Kinase Regulator Activity Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Regulation Of Cell Cycle Regulation Of Locomotion G1/S Transition Of Mitotic Cell Cycle Cell Cycle G1/S Phase Transition Sensory Perception Metanephric Glomerulus Vasculature Development Glycerol Transmembrane Transporter Activity Corticotropin Secretion Regulation Of Mitotic Cell Cycle Y Chromosome Positive Regulation Of Heterochromatin Formation Cyclin A1-CDK2 Complex Cyclin E2-CDK2 Complex Positive Regulation Of DNA-templated DNA Replication Initiation Acetylcholine Receptor Activator Activity Negative Regulation Of Developmental Growth Negative Regulation Of Cardiac Muscle Tissue Regeneration
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