BOLA2B and CCDC138

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BOLA2B	CCDC138
Description		bolA family member 2B	coiled-coil domain containing 138
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Iron-sulfur Cluster Assembly Complex
	Molecular Function	Protein Binding Iron-sulfur Cluster Binding 2 Iron, 2 Sulfur Cluster Binding	Protein Binding
	Biological Process	Intracellular Iron Ion Homeostasis Iron-sulfur Cluster Assembly [2Fe-2S] Cluster Assembly Cell Redox Homeostasis Protein Maturation
Pathways		Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)	Beard thickness ( 26926045) Monobrow thickness ( 26926045) Scalp hair shape ( 26926045)
Interacting Genes		32 interacting genes: ADAMTSL4 ANKRD55 BIRC2 BIRC7 C10orf55 C1orf94 CCDC138 CGGBP1 GLRX3 HDX ID3 IHO1 IL16 MBD3L1 MEOX2 MOBP NTAQ1 RAB4B RGS17 SLITRK5 TK1 TXNRD3 XIAP ZFP90 ZNF177 ZNF511 ZNF559-ZNF177 ZNF581 ZNF620 ZNF688 ZNF76 ZNF774	11 interacting genes: BOLA2 BOLA2B CDC37 CEP57 FAM161B KRT27 PIBF1 PKN1 TCEANC TRAF3IP3 UBAC1
Entrez ID		654483	165055
HPRD ID		19050	08136
Ensembl ID		ENSG00000169627	ENSG00000163006
Uniprot IDs		A0A499FJE1 Q9H3K6	Q96M89
PDB IDs
Enriched GO Terms of Interacting Partners?		Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Zinc Ion Binding Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of RNA Metabolic Process Positive Regulation Of Protein Polyubiquitination Protein Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Protein Polyubiquitination Positive Regulation Of Post-translational Protein Modification Negative Regulation Of Ripoptosome Assembly Involved In Necroptotic Process Metal Ion Binding Regulation Of Gene Expression Positive Regulation Of Protein Ubiquitination Cysteine-type Endopeptidase Inhibitor Activity Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Cellular Response To Leptomycin B Leptomycin B Binding Regulation Of Transcription By RNA Polymerase II Pigment Cell Development Protein-N-terminal Glutamine Amidohydrolase Activity Regulation Of Natural Killer Cell Apoptotic Process	Iron-sulfur Cluster Assembly Complex [2Fe-2S] Cluster Assembly 2 Iron, 2 Sulfur Cluster Binding Iron-sulfur Cluster Assembly Cell Redox Homeostasis Protein Maturation Intracellular Iron Ion Homeostasis Iron-sulfur Cluster Binding Negative Regulation Of Prostaglandin Biosynthetic Process HSP90-CDC37 Chaperone Complex
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