DEK and GPATCH11

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		DEK	GPATCH11
Name		DEK proto-oncogene	G-patch domain containing 11
Structure			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Contractile Muscle Fiber B-WICH Complex	Chromosome, Centromeric Region Kinetochore Chromosome
	Molecular Function	DNA Binding RNA Binding Protein Binding Histone Binding	Nucleic Acid Binding Protein Binding
	Biological Process	Chromatin Organization Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Signal Transduction Viral Genome Replication Positive Regulation Of Transcription By RNA Polymerase I Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase III Regulation Of Double-strand Break Repair Regulation Of Double-strand Break Repair Via Nonhomologous End Joining	None
Pathways		B-WICH complex positively regulates rRNA expression Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors Transcriptional regulation of granulopoiesis Transcriptional regulation of granulopoiesis	None
GWAS		Atrial fibrillation ( 30061737 ) Metabolite levels ( 23823483 ) PR interval ( 32439900 )	No GWAS studies recorded
Interacting Genes		16 interacting genes: AP2A1 CDC42 CEBPA CREBBP CSNK2A1 EP300 GPATCH11 H3-4 HLA-A KAT2B OGT SRRM1 TFAP2A TRIM55 TRIM63 ZIK1	5 interacting genes: ADGRB3 DEK PICK1 SDCBP ZNF474
Entrez ID		7913	253635
HPRD ID		00503	08785
Ensembl ID		ENSG00000124795	ENSG00000152133
Uniprot IDs		H0Y8X0 P35659	A0A6I8PRS5 Q8N954
PDB IDs		1Q1V 2JX3 8KCY 8KD1	Not available
GO Terms Enriched among Interactors		N-terminal Peptidyl-lysine Acetylation Histone Acetyltransferase Complex Peptidyl-lysine Acetylation N-terminal Protein Amino Acid Acetylation Regulation Of Glycolytic Process Regulation Of Carbohydrate Catabolic Process Acetyltransferase Activity Histone H3K27 Acetyltransferase Activity Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Chromatin DNA Binding Protein-lysine-acetyltransferase Activity Histone H3K18 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Histone Acetyltransferase Activity Protein Acetylation Rhythmic Process Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein Maturation L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Gluconeogenesis Histone H3 Acetyltransferase Activity Internal Peptidyl-lysine Acetylation Canonical NF-kappaB Signal Transduction DNA-binding Transcription Factor Binding Regulation Of Transcription By Glucose Internal Protein Amino Acid Acetylation STAT Family Protein Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein-containing Complex Chromatin Binding Regulation Of Cellular Response To Heat Response To Nutrient Levels Cellular Response To Nutrient Levels Positive Regulation Of Gene Expression Regulation Of Glucose Metabolic Process Learning Or Memory Cellular Response To Lectin Stimulatory C-type Lectin Receptor Signaling Pathway Negative Regulation Of Small Molecule Metabolic Process Sin3-type Complex Regulation Of Attachment Of Spindle Microtubules To Kinetochore Memory Cognition Transcription Coregulator Activity Negative Regulation Of Transcription By RNA Polymerase II	Cellular Component Maintenance Regulation Of Receptor Internalization Interleukin-5 Receptor Complex Regulation Of Receptor-mediated Endocytosis Interleukin-5 Receptor Binding