GPATCH11 and DEK

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GPATCH11	DEK
Description		G-patch domain containing 11	DEK proto-oncogene
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Chromosome	Nucleus Nucleoplasm Nucleolus Contractile Muscle Fiber B-WICH Complex
	Molecular Function	Nucleic Acid Binding Protein Binding	DNA Binding RNA Binding Protein Binding Histone Binding
	Biological Process		Chromatin Organization Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Signal Transduction Viral Genome Replication Positive Regulation Of Transcription By RNA Polymerase I Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase III Regulation Of Double-strand Break Repair Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways			B-WICH complex positively regulates rRNA expression Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors Transcriptional regulation of granulopoiesis Transcriptional regulation of granulopoiesis
Drugs
Diseases
GWAS			Atrial fibrillation ( 30061737) Metabolite levels ( 23823483) PR interval ( 32439900)
Interacting Genes		5 interacting genes: ADGRB3 DEK PICK1 SDCBP ZNF474	16 interacting genes: AP2A1 CDC42 CEBPA CREBBP CSNK2A1 EP300 GPATCH11 H3-4 HLA-A KAT2B OGT SRRM1 TFAP2A TRIM55 TRIM63 ZIK1
Entrez ID		253635	7913
HPRD ID		08785	00503
Ensembl ID		ENSG00000152133	ENSG00000124795
Uniprot IDs		A0A6I8PRS5 Q8N954	H0Y8X0 P35659
PDB IDs			1Q1V 2JX3 8KCY 8KD1
Enriched GO Terms of Interacting Partners?		Cellular Component Maintenance Regulation Of Receptor Internalization Interleukin-5 Receptor Complex Regulation Of Receptor-mediated Endocytosis Interleukin-5 Receptor Binding	N-terminal Peptidyl-lysine Acetylation Histone Acetyltransferase Complex Peptidyl-lysine Acetylation N-terminal Protein Amino Acid Acetylation Regulation Of Glycolytic Process Regulation Of Carbohydrate Catabolic Process Acetyltransferase Activity Histone H3K27 Acetyltransferase Activity Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Chromatin DNA Binding Protein-lysine-acetyltransferase Activity Histone H3K18 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Histone Acetyltransferase Activity Protein Acetylation Rhythmic Process Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein Maturation L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Gluconeogenesis Histone H3 Acetyltransferase Activity Internal Peptidyl-lysine Acetylation Canonical NF-kappaB Signal Transduction DNA-binding Transcription Factor Binding Regulation Of Transcription By Glucose Internal Protein Amino Acid Acetylation STAT Family Protein Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein-containing Complex Chromatin Binding Regulation Of Cellular Response To Heat Response To Nutrient Levels Cellular Response To Nutrient Levels Positive Regulation Of Gene Expression Regulation Of Glucose Metabolic Process Learning Or Memory Cellular Response To Lectin Stimulatory C-type Lectin Receptor Signaling Pathway Negative Regulation Of Small Molecule Metabolic Process Sin3-type Complex Regulation Of Attachment Of Spindle Microtubules To Kinetochore Memory Cognition Transcription Coregulator Activity Negative Regulation Of Transcription By RNA Polymerase II
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