NABP2 and PIGP

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		NABP2	PIGP
Description		nucleic acid binding protein 2	phosphatidylinositol glycan anchor biosynthesis class P
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Cytosol Site Of Double-strand Break SOSS Complex	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	DNA Binding Single-stranded DNA Binding Protein Binding C-rich Strand Telomeric DNA Binding DNA Polymerase Binding G-rich Strand Telomeric DNA Binding	Protein Binding Phosphatidylinositol N-acetylglucosaminyltransferase Activity
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Damage Response Response To Ionizing Radiation Mitotic G2/M Transition Checkpoint Establishment Of Protein Localization To Telomere Positive Regulation Of Telomere Capping	GPI Anchor Biosynthetic Process
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes	Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases
GWAS		Refractive error ( 32231278)
Interacting Genes		5 interacting genes: FBXL5 NBN PIGP RAD50 TP53	23 interacting genes: C1GALT1 CLK1 CNST DHRSX FIS1 IER3IP1 ITGAM LHFPL3 NABP2 NINJ2 PCMTD2 PLP1 PLP2 PTPN1 SCAMP5 SMAGP SNRNP70 THSD7B TMEM107 TMEM168 TMEM19 TMEM229B UBIAD1
Entrez ID		79035	51227
HPRD ID		14522	05806
Ensembl ID		ENSG00000139579	ENSG00000185808
Uniprot IDs		Q9BQ15	P57054
PDB IDs		4OWT 4OWW 4OWX 5D8E 5D8F 8RBZ
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Chromosomal Region Telomeric 3' Overhang Formation Mre11 Complex BRCA1-C Complex Negative Regulation Of Chromosome Organization Negative Regulation Of Telomere Capping Site Of Double-strand Break Regulation Of Telomere Maintenance R-loop Processing Regulation Of Cell Cycle G2/M Phase Transition Negative Regulation Of DNA Metabolic Process Regulation Of Telomere Capping DNA Strand Resection Involved In Replication Fork Processing Negative Regulation Of Mitotic Cell Cycle Phase Transition DNA Strand Elongation DNA Double-strand Break Processing Negative Regulation Of Mitotic Cell Cycle Double-strand Break Repair Negative Regulation Of Cell Cycle Phase Transition Replication Fork Regulation Of Chromosome Organization Negative Regulation Of Cell Cycle Process Homologous Recombination DNA Damage Response, Signal Transduction By P53 Class Mediator Neuroblast Proliferation Chromosome Organization Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Cell Cycle Mitotic G2/M Transition Checkpoint Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Mitotic DNA Damage Checkpoint Signaling Protein Serine/threonine Kinase Activator Activity Mitotic DNA Integrity Checkpoint Signaling Negative Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Telomere Maintenance Regulation Of DNA Metabolic Process Regulation Of Mitotic Cell Cycle DNA Repair Positive Regulation Of Organelle Organization Regulation Of Cellular Response To Stress Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Neural Precursor Cell Proliferation Positive Regulation Of Double-strand Break Repair DNA Damage Checkpoint Signaling Telomere Maintenance Signal Transduction By P53 Class Mediator Positive Regulation Of Chromosome Organization
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