PIGP and TMEM107

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PIGP	TMEM107
Description		phosphatidylinositol glycan anchor biosynthesis class P	transmembrane protein 107
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Cilium Membrane Ciliary Transition Zone MKS Complex Cell Projection
	Molecular Function	Protein Binding Phosphatidylinositol N-acetylglucosaminyltransferase Activity	Protein Binding
	Biological Process	GPI Anchor Biosynthetic Process	Detection Of Nodal Flow Determination Of Left/right Symmetry Regulation Of Gene Expression Neural Tube Patterning Cell Projection Organization Embryonic Digit Morphogenesis Cilium Organization Roof Of Mouth Development Cilium Assembly Craniofacial Suture Morphogenesis Protein Localization To Ciliary Transition Zone Non-motile Cilium Assembly
Pathways		Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases
GWAS			Diastolic blood pressure ( 30224653) Urinary potassium excretion ( 31409800)
Interacting Genes		23 interacting genes: C1GALT1 CLK1 CNST DHRSX FIS1 IER3IP1 ITGAM LHFPL3 NABP2 NINJ2 PCMTD2 PLP1 PLP2 PTPN1 SCAMP5 SMAGP SNRNP70 THSD7B TMEM107 TMEM168 TMEM19 TMEM229B UBIAD1	45 interacting genes: AQP3 AQP6 BIK CCL21 CD40 CD79A CLN8 CLSTN3 CPLX4 EBAG9 ERGIC3 EVI2B FAM209A FAM210B FCER1G GJA5 GJA8 GPX8 KCNA5 KCNJ6 LHFPL5 LMNA MGST3 MS4A3 PDZK1IP1 PGRMC2 PIGP SAR1A SLC10A6 SLC30A2 SLC35H1 SLC39A2 SYT2 THAP4 TMEM106A TMEM139 TMEM167B TMEM234 TMEM237 TMEM31 TMEM51 TMEM52B TMEM80 TMEM86B VMA21
Entrez ID		51227	84314
HPRD ID		05806	14400
Ensembl ID		ENSG00000185808	ENSG00000179029
Uniprot IDs		P57054	E9PIH0 Q6UX40
PDB IDs
Enriched GO Terms of Interacting Partners?			Membrane Transmembrane Transport Protein Binding Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Monoatomic Ion Transport Metal Ion Transport Renal Water Transport
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