ZP2 and ZPBP

Number of citations of the paper that reports this interaction (PMID 10924747)
0

Data Source:
HPRD (in vitro)

		ZP2	ZPBP
Gene Name		zona pellucida glycoprotein 2 (sperm receptor)	zona pellucida binding protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Multivesicular Body Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Membrane Secretory Granule Extracellular Matrix	Acrosomal Vesicle Zona Pellucida Receptor Complex Extracellular Region Nucleus Cell Body
	Molecular Function	Coreceptor Activity Acrosin Binding
	Biological Process	Manganese Ion Transport Intracellular Protein Transport Signal Transduction Single Fertilization Binding Of Sperm To Zona Pellucida Multicellular Organism Reproduction Regulation Of Acrosome Reaction Prevention Of Polyspermy	Acrosome Assembly Binding Of Sperm To Zona Pellucida
Pathways		Interaction With The Zona Pellucida Fertilization
Drugs
Diseases
GWAS			Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Total ventricular volume ( 21116278)
Protein-Protein Interactions		2 interactors: ACR ZPBP	2 interactors: CALU ZP2
Entrez ID		7783	11055
HPRD ID		01689	18364
Ensembl ID		ENSG00000103310	ENSG00000042813
Uniprot IDs		Q05996	Q9BS86
PDB IDs
Enriched GO Terms of Interacting Partners?		Binding Of Sperm To Zona Pellucida Sperm-egg Recognition Cell-cell Recognition Cell Recognition Single Fertilization Fertilization Acrosome Matrix Dispersal Sexual Reproduction Multicellular Organism Reproduction Acrosome Assembly Reproduction Acrosome Reaction Activation Of Adenylate Cyclase Activity Single Organism Reproductive Process Positive Regulation Of Adenylate Cyclase Activity Reproductive Process Secretory Granule Organization Calcium Ion-dependent Exocytosis Positive Regulation Of Lyase Activity Regulation Of Adenylate Cyclase Activity Positive Regulation Of CAMP Biosynthetic Process Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of CAMP Biosynthetic Process Regulation Of CAMP Metabolic Process Spermatid Development Spermatid Differentiation Vesicle Organization	Prevention Of Polyspermy Cell Activation Egg Activation Binding Of Sperm To Zona Pellucida Sperm-egg Recognition Cell-cell Recognition Platelet Degranulation Establishment Of Localization In Cell Cell Recognition Cellular Localization Single Fertilization Fertilization
Tagcloud ?		bird coat deglycosylated disc egg eggs enzymatically follicles germinal glycoproteins glycosylated granulosa heavily immature immunohistological maturing oocyte ovulated pellucida penetration preferential sperm surrounded yellow zona zp3 zp4 zpd
Tagcloud (Difference) ?		bird coat deglycosylated disc egg eggs enzymatically follicles germinal glycoproteins glycosylated granulosa heavily immature immunohistological maturing oocyte ovulated pellucida penetration preferential sperm surrounded yellow zona zp3 zp4 zpd
Tagcloud (Intersection) ?