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ZP2

Name zona pellucida glycoprotein 2
Structure PDB 8RKE
Interactors 2 interactors: ACR ZPBP
GO Annotations Cellular Component
  • Extracellular Region
  • Multivesicular Body
  • Endoplasmic Reticulum
  • Plasma Membrane
  • Membrane
  • Extracellular Matrix
  • Egg Coat
Molecular Function
  • Protein Binding
  • Coreceptor Activity
  • Acrosin Binding
  • Structural Constituent Of Egg Coat
  • Identical Protein Binding
Biological Process
  • Single Fertilization
  • Binding Of Sperm To Zona Pellucida
  • Regulation Of Acrosome Reaction
  • Prevention Of Polyspermy
Pathways
  • Interaction With Cumulus Cells And The Zona Pellucida
GWAS
  • Pelvic organ prolapse ( 26545240 )
Entrez ID 7783
HPRD ID 01689
Ensembl ID ENSG00000103310
Uniprot IDs Q05996
PDB IDs 8RKE 8RKF
GO Terms Enriched among Interactors ?
  • Binding Of Sperm To Zona Pellucida
  • Sperm-egg Recognition
  • Cell-cell Recognition
  • Acrosomal Vesicle
  • Cell Recognition
  • Acrosome Matrix Dispersal
  • Amidase Activity
  • Acrosomal Matrix
  • Fucose Binding
  • Zona Pellucida Receptor Complex
  • Penetration Of Zona Pellucida
  • Activation Of Adenylate Cyclase Activity
  • Positive Regulation Of Adenylate Cyclase Activity
  • Acrosome Reaction
  • Golgi-associated Vesicle
  • Positive Regulation Of Lyase Activity
  • Positive Regulation Of Cyclase Activity
  • D-mannose Binding
  • Acrosomal Membrane
  • Acrosome Assembly
  • Copper Ion Binding
  • Reproductive Process
  • Secretory Granule Organization
  • Single Fertilization
  • Protease Binding
  • Serine-type Peptidase Activity
  • Extracellular Region
  • Fertilization
  • Serine-type Endopeptidase Activity

© Madhavi K. Ganapathiraju 2012-2026