ZPBP and ZP2

Number of citations of the paper that reports this interaction (PMID 10924747)
0

Data Source:
HPRD (in vitro)

		ZPBP	ZP2
Gene Name		zona pellucida binding protein	zona pellucida glycoprotein 2 (sperm receptor)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Acrosomal Vesicle Zona Pellucida Receptor Complex Extracellular Region Nucleus Cell Body	Extracellular Region Proteinaceous Extracellular Matrix Multivesicular Body Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Membrane Secretory Granule Extracellular Matrix
	Molecular Function		Coreceptor Activity Acrosin Binding
	Biological Process	Acrosome Assembly Binding Of Sperm To Zona Pellucida	Manganese Ion Transport Intracellular Protein Transport Signal Transduction Single Fertilization Binding Of Sperm To Zona Pellucida Multicellular Organism Reproduction Regulation Of Acrosome Reaction Prevention Of Polyspermy
Pathways			Interaction With The Zona Pellucida Fertilization
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Total ventricular volume ( 21116278)
Protein-Protein Interactions		2 interactors: CALU ZP2	2 interactors: ACR ZPBP
Entrez ID		11055	7783
HPRD ID		18364	01689
Ensembl ID		ENSG00000042813	ENSG00000103310
Uniprot IDs		Q9BS86	Q05996
PDB IDs
Enriched GO Terms of Interacting Partners?		Prevention Of Polyspermy Cell Activation Egg Activation Binding Of Sperm To Zona Pellucida Sperm-egg Recognition Cell-cell Recognition Platelet Degranulation Establishment Of Localization In Cell Cell Recognition Cellular Localization Single Fertilization Fertilization	Binding Of Sperm To Zona Pellucida Sperm-egg Recognition Cell-cell Recognition Cell Recognition Single Fertilization Fertilization Acrosome Matrix Dispersal Sexual Reproduction Multicellular Organism Reproduction Acrosome Assembly Reproduction Acrosome Reaction Activation Of Adenylate Cyclase Activity Single Organism Reproductive Process Positive Regulation Of Adenylate Cyclase Activity Reproductive Process Secretory Granule Organization Calcium Ion-dependent Exocytosis Positive Regulation Of Lyase Activity Regulation Of Adenylate Cyclase Activity Positive Regulation Of CAMP Biosynthetic Process Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of CAMP Biosynthetic Process Regulation Of CAMP Metabolic Process Spermatid Development Spermatid Differentiation Vesicle Organization
Tagcloud ?			bird coat deglycosylated disc egg eggs enzymatically follicles germinal glycoproteins glycosylated granulosa heavily immature immunohistological maturing oocyte ovulated pellucida penetration preferential sperm surrounded yellow zona zp3 zp4 zpd
Tagcloud (Difference) ?			bird coat deglycosylated disc egg eggs enzymatically follicles germinal glycoproteins glycosylated granulosa heavily immature immunohistological maturing oocyte ovulated pellucida penetration preferential sperm surrounded yellow zona zp3 zp4 zpd
Tagcloud (Intersection) ?