CD52

Description		CD52 molecule
Image
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane Sperm Midpiece Side Of Membrane
	Molecular Function
	Biological Process	Positive Regulation Of Cytosolic Calcium Ion Concentration Respiratory Burst
Pathways		Post-translational modification: synthesis of GPI-anchored proteins
Drugs		Alemtuzumab
Diseases
GWAS		Eosinophil count ( 32888494) Monocyte percentage of white cells ( 27863252)
Interacting Genes		4 interacting genes: AQP6 CMTM2 LMNA SLC30A2
Entrez ID		1043
HPRD ID		00257
Ensembl ID		ENSG00000169442
Uniprot IDs		P31358 V9HWN9
PDB IDs		6OBD
Enriched GO Terms of Interacting Partners?		PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport DNA Double-strand Break Attachment To Nuclear Envelope Structural Constituent Of Nuclear Lamina Zinc Ion Import Into Zymogen Granule Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Lamin Filament Nuclear Pore Localization Zinc:proton Antiporter Activity Zinc Ion Import Into Lysosome Zinc Export Across Plasma Membrane Monoatomic Anion Channel Activity Renal Water Transport Negative Regulation Of Mesenchymal Cell Proliferation Vacuolar Transmembrane Transport Ammonium Transmembrane Transport Ammonium Channel Activity Ventricular Cardiac Muscle Cell Development Zinc Ion Import Into Organelle Secretory Vesicle Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Nuclear Lamina Water Channel Activity Protein Localization To Nuclear Envelope Carbon Dioxide Transport Zymogen Granule Membrane Monoatomic Cation Transmembrane Transporter Activity Negative Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Nuclear Envelope Organization Zinc Ion Transmembrane Transporter Activity One-carbon Compound Transport Water Transport Nuclear Migration Zinc Ion Transport Zinc Ion Transmembrane Transport Inorganic Cation Transmembrane Transport Nucleus Localization Intracellular Zinc Ion Homeostasis Fluid Transport Regulation Of Mesenchymal Cell Proliferation Inorganic Ion Transmembrane Transport Channel Activity Nuclear Lumen Negative Regulation Of Muscle Hypertrophy
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