CACNA1D and CALB1

Number of citations of the paper that reports this interaction (PMID 17257825)
5

Data Source:
BioGRID (pull down)

		CACNA1D	CALB1
Gene Name		calcium channel, voltage-dependent, L type, alpha 1D subunit	calbindin 1, 28kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Voltage-gated Calcium Channel Complex Z Disc	Nucleus Cytosol Axon Dendrite Neuronal Cell Body Synapse Extracellular Vesicular Exosome
	Molecular Function	Voltage-gated Calcium Channel Activity High Voltage-gated Calcium Channel Activity Ankyrin Binding Metal Ion Binding Alpha-actinin Binding Voltage-gated Calcium Channel Activity Involved In Cardiac Muscle Cell Action Potential Voltage-gated Calcium Channel Activity Involved SA Node Cell Action Potential	Vitamin D Binding Calcium Ion Binding Protein Binding Zinc Ion Binding
	Biological Process	Energy Reserve Metabolic Process Calcium Ion Transport Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Axon Guidance Sensory Perception Of Sound Small Molecule Metabolic Process Regulation Of Insulin Secretion Positive Regulation Of Calcium Ion Transport Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization Calcium Ion Import Calcium Ion Transmembrane Transport Membrane Depolarization During Action Potential Membrane Depolarization During Cardiac Muscle Cell Action Potential Membrane Depolarization During SA Node Cell Action Potential Membrane Repolarization During SA Node Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Potassium Ion Transmembrane Transport	Short-term Memory Long-term Memory Locomotory Behavior Retina Layer Formation Metanephric Part Of Ureteric Bud Development Regulation Of Synaptic Plasticity Cytosolic Calcium Ion Homeostasis Cellular Response To Organic Substance Metanephric Collecting Duct Development Metanephric Distal Convoluted Tubule Development Metanephric Connecting Tubule Development
Pathways		NCAM1 interactions Axon guidance Integration of energy metabolism Regulation of insulin secretion NCAM signaling for neurite out-growth Adrenaline,noradrenaline inhibits insulin secretion
Drugs
Diseases
GWAS		Insulin resistance/response ( 21901158) Refractive error ( 23396134) Ventricular conduction ( 21076409)
Protein-Protein Interactions		3 interactors: CALB1 FGFR2 STX1A	6 interactors: CACNA1D IKBKG IMPA1 RANBP9 TRPV5 TRPV6
Entrez ID		776	793
HPRD ID		00247	00229
Ensembl ID		ENSG00000157388	ENSG00000104327
Uniprot IDs		Q01668 Q59GD8	B7Z9J4 P05937
PDB IDs		3LV3
Enriched GO Terms of Interacting Partners?		Synaptic Vesicle Transport Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development Coronal Suture Morphogenesis Metanephric Connecting Tubule Development Fibroblast Growth Factor Receptor Signaling Pathway Involved In Positive Regulation Of Cell Proliferation In Bone Marrow Fibroblast Growth Factor Receptor Signaling Pathway Involved In Hemopoiesis Fibroblast Growth Factor Receptor Signaling Pathway Involved In Negative Regulation Of Apoptotic Process In Bone Marrow Kidney Epithelium Development Establishment Of Vesicle Localization Vesicle Localization Negative Regulation Of Apoptotic Process In Bone Marrow Squamous Basal Epithelial Stem Cell Differentiation Involved In Prostate Gland Acinus Development Mesenchymal Cell Differentiation Involved In Lung Development Fibroblast Growth Factor Receptor Signaling Pathway Involved In Mammary Gland Specification Mammary Gland Bud Formation Branch Elongation Involved In Salivary Gland Morphogenesis Endodermal Digestive Tract Morphogenesis Fibroblast Growth Factor Receptor Signaling Pathway Involved In Orbitofrontal Cortex Development Metanephric Part Of Ureteric Bud Development Regulation Of Synaptic Transmission Kidney Development Establishment Of Organelle Localization Renal System Development Ventricular Zone Neuroblast Division Branching Morphogenesis Of A Nerve Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Prostate Epithelial Cord Elongation Orbitofrontal Cortex Development Metanephric Distal Convoluted Tubule Development Mammary Gland Specification Mammary Gland Bud Morphogenesis Camera-type Eye Development Urogenital System Development Positive Regulation Of Cell Proliferation In Bone Marrow Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Eye Development Forebrain Ventricular Zone Progenitor Cell Division Metanephric Distal Tubule Development Mesenchymal Cell Proliferation Involved In Lung Development Organelle Localization Membranous Septum Morphogenesis Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Docking Lateral Sprouting From An Epithelium Limb Bud Formation Lacrimal Gland Development Metanephric Collecting Duct Development	Calcium Ion Transmembrane Transport Calcium Ion Transport Membrane Repolarization During SA Node Cell Action Potential Metal Ion Transport Cation Transmembrane Transport Membrane Depolarization During SA Node Cell Action Potential Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization SA Node Cell Action Potential Inositol Biosynthetic Process Cation Transport SA Node Cell To Atrial Cardiac Muscle Cell Communication Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Inositol Phosphate Dephosphorylation Ion Transmembrane Transport Phosphorylated Carbohydrate Dephosphorylation Membrane Depolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization Axon Guidance Cell-cell Signaling Involved In Cardiac Conduction
Tagcloud ?		bmp ccl2 cd25 cd26 cdkn1a cml cure dpp4 dusp12 dysregulation eradication exploited il1rap il2ra kcnk5 lscs marcks microarrays mycn oncogenes perp persistence ptprd refined slc4a4 timeless tki transcriptome withdrawal	accounts brown call creeping cutoffs egg eggshell empirical footprints gal gaps heterozygosity hypotheses insr lepr localizing moving nramp1 outliers permutation prlhr scanned sliding statistic subjectively sweeps tails window windows
Tagcloud (Difference) ?		bmp ccl2 cd25 cd26 cdkn1a cml cure dpp4 dusp12 dysregulation eradication exploited il1rap il2ra kcnk5 lscs marcks microarrays mycn oncogenes perp persistence ptprd refined slc4a4 timeless tki transcriptome withdrawal	accounts brown call creeping cutoffs egg eggshell empirical footprints gal gaps heterozygosity hypotheses insr lepr localizing moving nramp1 outliers permutation prlhr scanned sliding statistic subjectively sweeps tails window windows
Tagcloud (Intersection) ?