ZKSCAN8 and ZNF174

Number of citations of the paper that reports this interaction (PMID 10567577)
17

Data Source:
BioGRID (two hybrid)

		ZKSCAN8	ZNF174
Gene Name		zinc finger with KRAB and SCAN domains 8	zinc finger protein 174
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Actin Cytoskeleton
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Sequence-specific DNA Binding Transcription Factor Activity Protein Homodimerization Activity Transcription Regulatory Region DNA Binding Metal Ion Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: PRNP ZNF165 ZNF174 ZNF24	6 interactors: CDK6 MZF1 ZKSCAN8 ZNF20 ZNF24 ZSCAN32
Entrez ID		7745	7727
HPRD ID		03760	04876
Ensembl ID		ENSG00000198315	ENSG00000103343
Uniprot IDs		B4DYF1 Q15776 Q59HG5	Q15697
PDB IDs			1Y7Q
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To Copper Ion Negative Regulation Of Calcium-mediated Signaling Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Interleukin-17 Production Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Gene Expression Negative Regulation Of Activated T Cell Proliferation Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Interleukin-2 Production Cellular Copper Ion Homeostasis Negative Regulation Of T Cell Receptor Signaling Pathway Transcription, DNA-templated Response To Copper Ion Copper Ion Homeostasis RNA Biosynthetic Process Negative Regulation Of Interferon-gamma Production Regulation Of Activated T Cell Proliferation Regulation Of Potassium Ion Transmembrane Transport Regulation Of Calcium-mediated Signaling Regulation Of T Cell Receptor Signaling Pathway RNA Metabolic Process Response To Cadmium Ion Regulation Of Metabolic Process Regulation Of Potassium Ion Transport Negative Regulation Of T Cell Proliferation Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Cellular Macromolecule Biosynthetic Process Negative Regulation Of Leukocyte Proliferation Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Interferon-gamma Production Negative Regulation Of T Cell Activation Negative Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Homotypic Cell-cell Adhesion	Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression RNA Metabolic Process Cell Dedifferentiation Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Senescence Nitrogen Compound Metabolic Process Hematopoietic Stem Cell Differentiation Negative Regulation Of Cell Aging Dentate Gyrus Development Type B Pancreatic Cell Development Astrocyte Development Type B Pancreatic Cell Differentiation Lateral Ventricle Development Enteroendocrine Cell Differentiation Cellular Metabolic Process Regulation Of Cellular Senescence Glandular Epithelial Cell Development Regulation Of Erythrocyte Differentiation Astrocyte Differentiation Ventricular System Development Columnar/cuboidal Epithelial Cell Development Glandular Epithelial Cell Differentiation Negative Regulation Of Osteoblast Differentiation Endocrine Pancreas Development Positive Regulation Of Cell-matrix Adhesion Regulation Of Cellular Process Positive Regulation Of Fibroblast Proliferation T Cell Differentiation In Thymus Transcription From RNA Polymerase II Promoter Hippocampus Development
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