ZKSCAN8

Name	zinc finger with KRAB and SCAN domains 8
Structure	No pdb structure
Interactors	10 interactors: APP FBXO7 MAGOH OGT PRNP TCEA2 ZNF165 ZNF174 ZNF24 ZNF587
GO Annotations	Cellular Component	Nucleus Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways	Generic Transcription Pathway
GWAS	Alanine aminotransferase levels ( 33547301 ) Asthma and major depressive disorder ( 31619474 ) Autism spectrum disorder or schizophrenia ( 28540026 ) Brain morphology (MOSTest) ( 32665545 ) Fish- and plant-related diet ( 32066663 ) Mean corpuscular volume ( 27863252 ) Refractive error ( 32231278 ) Smoking status (ever vs never smokers) ( 30643258 ) Subcortical volume (MOSTest) ( 32665545 )
Entrez ID	7745
HPRD ID	03760
Ensembl ID	ENSG00000198315
Uniprot IDs	Q15776 Q59HG5
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Neuron Projection Maintenance Regulation Of Dendritic Spine Maintenance Negative Regulation Of Long-term Synaptic Potentiation Regulation Of Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Intracellular Copper Ion Homeostasis Copper Ion Homeostasis Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Cellular Response To Copper Ion Regulation Of Primary Metabolic Process Molecular Function Activator Activity Response To Copper Ion Regulation Of Macromolecule Metabolic Process Amyloid-beta Complex Regulation Of Amyloid Precursor Protein Catabolic Process Growth Cone Lamellipodium Neuron Projection Organization Regulation Of Neuron Apoptotic Process DNA Binding Negative Regulation Of RNA Biosynthetic Process Regulation Of Response To Calcium Ion Positive Regulation Of Calcium-mediated Signaling Regulation Of Glycolytic Process Amylin Binding Response To Amyloid-beta Positive Regulation Of Toll Signaling Pathway Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Cellular Response To Amyloid-beta Type 8 Metabotropic Glutamate Receptor Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Regulation Of Synapse Organization Regulation Of Carbohydrate Catabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Neuron Apoptotic Process Autophagy Of Mitochondrion Regulation Of ATP Metabolic Process Nucleus