TRIM26 and USP36

Number of citations of the paper that reports this interaction (PMID 23105109)
4

Data Source:
BioGRID (two hybrid)

		TRIM26	USP36
Gene Name		tripartite motif containing 26	ubiquitin specific peptidase 36
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Cytosol	Nucleus Nucleolus
	Molecular Function	DNA Binding Zinc Ion Binding Metal Ion Binding	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Poly(A) RNA Binding
	Biological Process	Cytokine-mediated Signaling Pathway Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Negative Regulation Of Viral Release From Host Cell	Protein Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system
Drugs
Diseases
GWAS		Schizophrenia ( 21926974 22883433)
Protein-Protein Interactions		15 interactors: AES MNAT1 OTUB2 PHF7 RABEP1 RNF10 RNF126 THAP1 TRIM41 UBE2D1 UBE2D2 UBE2D3 USP36 USP39 USP5	2 interactors: NPM1 TRIM26
Entrez ID		7726	57602
HPRD ID		02901	07164
Ensembl ID		ENSG00000234127	ENSG00000055483
Uniprot IDs		Q12899	Q9P275
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Modification-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein Ubiquitination Proteolysis Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Cellular Protein Metabolic Process Catabolic Process Protein Polyubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Toll-like Receptor 4 Signaling Pathway Protein Metabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein Deubiquitination Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Protein K48-linked Deubiquitination Protein Modification By Small Protein Removal Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Transcription Initiation From RNA Polymerase II Promoter Cellular Metabolic Process Positive Regulation Of Innate Immune Response Regulation Of Proteasomal Protein Catabolic Process Protein Monoubiquitination DNA-templated Transcription, Initiation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Innate Immune Response Response To Hypoxia Cytoplasm-associated Proteasomal Ubiquitin-dependent Protein Catabolic Process BMP Signaling Pathway RNA Metabolic Process Transcription, DNA-templated Cellular Response To Stress Regulation Of Protein Catabolic Process RNA Biosynthetic Process	Regulation Of Endoribonuclease Activity Regulation Of EIF2 Alpha Phosphorylation By DsRNA Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Ribonuclease Activity Regulation Of Endodeoxyribonuclease Activity Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Regulation Of Centriole Replication Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Centrosome Duplication Negative Regulation Of Viral Entry Into Host Cell Regulation Of Viral Entry Into Host Cell Regulation Of Viral Release From Host Cell CENP-A Containing Nucleosome Assembly Ribosome Assembly Histone Exchange DNA Replication-independent Nucleosome Assembly Cellular Response To DsRNA Regulation Of Centrosome Duplication Regulation Of Centrosome Cycle Centromere Complex Assembly Centrosome Cycle ATP-dependent Chromatin Remodeling Cell Aging Response To DsRNA Positive Regulation Of Translation Negative Regulation Of Viral Process Cellular Response To Organic Substance Centrosome Organization Microtubule Organizing Center Organization Nucleosome Assembly Positive Regulation Of NF-kappaB Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Chromatin Assembly Response To Organic Substance Nucleosome Organization Regulation Of Microtubule Cytoskeleton Organization Cellular Response To Interferon-gamma Chromatin Assembly Or Disassembly Regulation Of Viral Process Negative Regulation Of Cytoskeleton Organization Protein-DNA Complex Assembly Response To Interferon-gamma Regulation Of Microtubule-based Process Ribonucleoprotein Complex Assembly Chromatin Remodeling DNA Packaging Ribosome Biogenesis
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