RELL1 and OXSR1

Number of citations of the paper that reports this interaction (PubMedID 16389068)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		RELL1	OXSR1
Description		RELT like 1	oxidative stress responsive kinase 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Microtubule Cytoskeleton Membrane	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding	Nucleotide Binding Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Potassium Channel Inhibitor Activity Protein Kinase Binding Identical Protein Binding Transmembrane Transporter Binding Metal Ion Binding Ion Channel Regulator Activity Protein Serine Kinase Activity
	Biological Process	Positive Regulation Of P38MAPK Cascade	Protein Phosphorylation Cell Volume Homeostasis Response To Oxidative Stress Signal Transduction Osmosensory Signaling Pathway Response To Xenobiotic Stimulus Positive Regulation Of T Cell Chemotaxis Intracellular Signal Transduction Chemokine (C-C Motif) Ligand 21 Signaling Pathway Chemokine (C-X-C Motif) Ligand 12 Signaling Pathway Protein Autophosphorylation Renal Sodium Ion Absorption Cellular Hyperosmotic Response Cellular Hypotonic Response Potassium Ion Transmembrane Transport Negative Regulation Of Potassium Ion Transmembrane Transport Cellular Response To Chemokine
Pathways
Drugs			Fostamatinib
Diseases
GWAS		Staphylococcus aureus nasal carriage (intermittent) ( 26569114)	Gut microbiota (bacterial taxa) ( 27723756) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		4 interacting genes: OXSR1 RELL2 RELT TREX1	14 interacting genes: AKT1 APP BMPR1B OGT PAK1 RELL1 SLC12A1 SLC12A2 SLC12A6 SMURF1 TGFBR1 WNK1 WNK2 WNK4
Entrez ID		768211	9943
HPRD ID		19252	06809
Ensembl ID		ENSG00000181826	ENSG00000172939
Uniprot IDs		Q8IUW5	O95747
PDB IDs			2V3S 2VWI 3DAK 7OKW
Enriched GO Terms of Interacting Partners?		Cellular Response To Type I Interferon DNA Exonuclease Activity Immune Complex Formation Adenyl Deoxyribonucleotide Binding Immune Response In Brain Or Nervous System Retrotransposition Transposition Osmosensory Signaling Pathway Hypotonic Response Cytokine-mediated Signaling Pathway Chemokine (C-X-C Motif) Ligand 12 Signaling Pathway Ion Channel Regulator Activity Magnesium Ion Binding Cellular Hypotonic Response Cellular Response To Chemokine Cellular Response To Cytokine Stimulus Response To Oxidative Stress Cellular Response To Chemical Stress Potassium Channel Inhibitor Activity Positive Regulation Of T Cell Chemotaxis Regulation Of T Cell Chemotaxis Chemokine (C-C Motif) Ligand 21 Signaling Pathway Regulation Of Protein Complex Stability Cellular Response To Hydroxyurea Lymphoid Progenitor Cell Differentiation Regulation Of Lysosome Organization Mitotic G1 DNA Damage Checkpoint Signaling T Cell Antigen Processing And Presentation MutSalpha Complex Binding Response To Hydroxyurea Negative Regulation Of CGAS/STING Signaling Pathway 3'-5'-DNA Exonuclease Activity DNA Binding, Bending Atrial Cardiac Muscle Tissue Development DNA Synthesis Involved In UV-damage Excision Repair Response To Type I Interferon 3'-5' Exonuclease Activity Double-stranded DNA 3'-5' DNA Exonuclease Activity MutLalpha Complex Binding Oligosaccharyltransferase Complex Amelogenesis Mitotic G1/S Transition Checkpoint Signaling Cellular Hyperosmotic Response Positive Regulation Of Lymphocyte Chemotaxis Nuclear Replication Fork Macrophage Activation Involved In Immune Response Response To Peptide Hyperosmotic Response Negative Regulation Of Potassium Ion Transmembrane Transport Renal Sodium Ion Transport	Monoatomic Anion Homeostasis Chloride Ion Homeostasis Chemical Homeostasis Protein Serine/threonine Kinase Activity Cell Volume Homeostasis Potassium Ion Homeostasis Chloride:monoatomic Cation Symporter Activity Intracellular Chloride Ion Homeostasis Monoatomic Ion Homeostasis Protein Kinase Activity Potassium Ion Transmembrane Transport Potassium Ion Transport Membrane Regulation Of Sodium Ion Transport Transferase Activity Homeostatic Process Kinase Activity Regulation Of Cell Size Cellular Homeostasis Response To Stress Inorganic Ion Homeostasis Sodium:potassium:chloride Symporter Activity Chloride Transport Potassium Ion Transmembrane Transporter Activity Protein-containing Complex Monoatomic Cation Homeostasis Positive Regulation Of Signal Transduction Negative Regulation Of Multicellular Organismal Process Intracellular Chemical Homeostasis Protein Metabolic Process Sodium Ion Transmembrane Transport Regulation Of Developmental Growth Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Multicellular Organismal Process Transforming Growth Factor Beta Receptor Activity, Type I Inorganic Anion Transport Monoatomic Anion Transport Negative Regulation Of Pancreatic Juice Secretion Regulation Of Protein Localization Potassium Ion Import Across Plasma Membrane Positive Regulation Of Developmental Process Metal Ion Transport Regulation Of Developmental Process Regulation Of Protein Localization To Cell Periphery Protein Phosphorylation Inorganic Cation Transmembrane Transport Regulation Of Metal Ion Transport Regulation Of Spontaneous Synaptic Transmission SMAD Binding
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