ZNF8 and ZNF114

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF8	ZNF114
Description		zinc finger protein 8	zinc finger protein 114
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription BMP Signaling Pathway	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS
Interacting Genes		8 interacting genes: AP1M1 MCRS1 SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 ZNF114	10 interacting genes: CENATAC CLIP4 KIAA0753 KLHL2 KRTAP10-6 MAP7 MYO15B SUFU TPPP ZNF8
Entrez ID		7554	163071
HPRD ID		01919	14463
Ensembl ID		ENSG00000278129	ENSG00000178150
Uniprot IDs		B3KS94 P17098	Q8NC26
PDB IDs
Enriched GO Terms of Interacting Partners?		SMAD Protein Complex Heteromeric SMAD Protein Complex I-SMAD Binding SMAD Protein Signal Transduction Embryonic Pattern Specification Transforming Growth Factor Beta Receptor Signaling Pathway Ureteric Bud Development Mesonephric Epithelium Development Mesonephric Tubule Development DEAD/H-box RNA Helicase Binding Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Co-SMAD Binding Primary MiRNA Processing Tube Development Kidney Epithelium Development Transcription Regulator Complex Cardiac Conduction System Development Response To Growth Factor Homomeric SMAD Protein Complex R-SMAD Binding Osteoblast Differentiation Activin Receptor Signaling Pathway Pattern Specification Process Endoderm Development MiRNA Processing Osteoblast Fate Commitment Activin Responsive Factor Complex Paraxial Mesoderm Morphogenesis Cell Fate Commitment RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Gastrulation DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Anti-Mullerian Hormone Receptor Signaling Pathway Positive Regulation Of MiRNA Transcription Mesoderm Morphogenesis Epithelium Development Positive Regulation Of Epithelial To Mesenchymal Transition Cardiac Muscle Tissue Development Positive Regulation Of MiRNA Metabolic Process Pericardium Development Intracellular Iron Ion Homeostasis Positive Regulation Of Transcription By RNA Polymerase II Enzyme-linked Receptor Protein Signaling Pathway Response To Transforming Growth Factor Beta Trophoblast Cell Migration DNA-binding Transcription Factor Activity Cellular Response To Growth Factor Stimulus Regulation Of MiRNA Transcription Regulation Of Transforming Growth Factor Beta2 Production	Cytoskeleton Microtubule-based Process Postsynaptic Golgi Apparatus Cytoplasmic Microtubule Organization Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification Regulation Of Cellular Response To Drug Positive Regulation Of Cellular Response To Drug Positive Regulation Of Response To Drug Microtubule Organizing Center
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