TRPV2 and TRPV1

Number of citations of the paper that reports this interaction (PMID 16115206)
25

Data Source:
HPRD (in vivo)

		TRPV2	TRPV1
Gene Name		transient receptor potential cation channel, subfamily V, member 2	transient receptor potential cation channel, subfamily V, member 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Endomembrane System Growth Cone Membrane Melanosome Axonal Growth Cone Cell Body	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Cell Junction Intrinsic Component Of Plasma Membrane Dendritic Spine Membrane Postsynaptic Membrane
	Molecular Function	Ion Channel Activity Cation Channel Activity Calcium Channel Activity Ion Transmembrane Transporter Activity	Transmembrane Signaling Receptor Activity Excitatory Extracellular Ligand-gated Ion Channel Activity Calcium Channel Activity Calmodulin Binding ATP Binding Calcium-release Channel Activity Phosphoprotein Binding
	Biological Process	Transport Sensory Perception Response To Temperature Stimulus Response To Heat Ion Transmembrane Transport Positive Regulation Of Axon Extension Transmembrane Transport Calcium Ion Transmembrane Transport Positive Regulation Of Calcium Ion Import	Transport Cell Surface Receptor Signaling Pathway Chemosensory Behavior Ion Transmembrane Transport Thermoception Transmembrane Transport Calcium Ion Transmembrane Transport Cellular Response To Alkaloid Cellular Response To ATP
Pathways		Ion channel transport TRP channels Stimuli-sensing channels	Ion channel transport TRP channels Stimuli-sensing channels
Drugs			Alpha-Linolenic Acid Icosapent Aspartame
Diseases
GWAS
Protein-Protein Interactions		2 interactors: SLC50A1 TRPV1	7 interactors: CALM1 EGFR ITCH PRKCE SNAPIN SYT9 TRPV2
Entrez ID		51393	7442
HPRD ID		05980	03648
Ensembl ID		ENSG00000187688	ENSG00000196689
Uniprot IDs		Q9Y5S1	E7EQ78 Q8NER1
PDB IDs		2F37
Enriched GO Terms of Interacting Partners?		Glucoside Transport Thermoception Cellular Response To ATP Chemosensory Behavior Positive Regulation Of Gene Expression, Epigenetic Response To ATP Sensory Perception Of Temperature Stimulus Cellular Response To Alkaloid Carbohydrate Derivative Transport Transmembrane Transport	Positive Regulation Of Transport Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Positive Regulation Of Phospholipase Activity Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Regulation Of Cellular Localization Immune Response-regulating Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Innate Immune Response Regulation Of Nitric-oxide Synthase Activity Fc Receptor Signaling Pathway Regulation Of Immune Response Negative Regulation Of Transporter Activity Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Transmembrane Transport Regulation Of Cytokinesis Immune Response-regulating Cell Surface Receptor Signaling Pathway Response To Abiotic Stimulus Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Ion Transmembrane Transport Regulation Of Intracellular Transport Regulation Of Oxidoreductase Activity Positive Regulation Of Ion Transmembrane Transport Immune Response Regulation Of Immune System Process Regulation Of Phosphorylation Regulation Of Cellular Ketone Metabolic Process Alkanesulfonate Metabolic Process Positive Regulation Of Late Endosome To Lysosome Transport Positive Regulation Of Cellular Glucuronidation Defense Response Positive Regulation Of Calcium Ion Transport Calcium-mediated Signaling Negative Regulation Of Ion Transport Positive Regulation Of Synaptic Transmission Regulation Of Phosphorus Metabolic Process Reactive Oxygen Species Metabolic Process Cellular Response To Growth Factor Stimulus Response To Calcium Ion Response To Growth Factor Regulation Of MAPK Cascade TRAM-dependent Toll-like Receptor 4 Signaling Pathway Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling
Tagcloud ?		4alpha abundantly adipogenesis adipogenic aminoethoxydiphenyl blocker borate channels clamp confocal dicaprinate erk1 etc individually lipodystrophy oscillations patch phorbol phosphorylating physiology pipette preadipocytes probenecid rn ruthenium trpm7 trpv4 voltage	6h ag anandamide arachidonoylglycerol ascaris beagle cannabinoid capsaicin cb1 cb2 congener dependently desensitization desensitized dogs endocannabinoid hek hypersensitive ic50 keratinocytes micronized mum palmitoylethanolamide pea spontaneously suum ultramicronized vanilloid volunteers
Tagcloud (Difference) ?		4alpha abundantly adipogenesis adipogenic aminoethoxydiphenyl blocker borate channels clamp confocal dicaprinate erk1 etc individually lipodystrophy oscillations patch phorbol phosphorylating physiology pipette preadipocytes probenecid rn ruthenium trpm7 trpv4 voltage	6h ag anandamide arachidonoylglycerol ascaris beagle cannabinoid capsaicin cb1 cb2 congener dependently desensitization desensitized dogs endocannabinoid hek hypersensitive ic50 keratinocytes micronized mum palmitoylethanolamide pea spontaneously suum ultramicronized vanilloid volunteers
Tagcloud (Intersection) ?