MRPL49 and OXA1L

Number of citations of the paper that reports this interaction (PubMedID 20601428)
45

Data Source:
BioGRID (pull down)

		MRPL49	OXA1L
Description		mitochondrial ribosomal protein L49	OXA1L mitochondrial inner membrane insertase
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Large Ribosomal Subunit Ribosome Ribonucleoprotein Complex	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Mitochondrial Membrane Protein-containing Complex
	Molecular Function	Structural Constituent Of Ribosome Protein Binding	Protein Binding Membrane Insertase Activity Protein Homodimerization Activity Mitochondrial Ribosome Binding
	Biological Process	Translation Mitochondrial Translation	Aerobic Respiration Mitochondrial Translation Negative Regulation Of ATP-dependent Activity Protein Insertion Into Mitochondrial Inner Membrane From Matrix Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial Proton-transporting ATP Synthase Complex Assembly Protein Tetramerization Negative Regulation Of Oxidoreductase Activity Mitochondrial Protein Quality Control
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Complex I biogenesis Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS			Intraocular pressure ( 30591961) Metabolite levels ( 23823483) Response to hepatitis B vaccine ( 29534301)
Interacting Genes		5 interacting genes: APP CDC42 GABARAPL2 OXA1L YAP1	6 interacting genes: CBLC MRPL20 MRPL28 MRPL48 MRPL49 MRPL51
Entrez ID		740	5018
HPRD ID		06037	03043
Ensembl ID		ENSG00000149792	ENSG00000155463
Uniprot IDs		Q13405	J3KNA0 Q15070 Q2M1J6
PDB IDs		3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5H 7A5I 7A5J 7A5K 7L08 7L20 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF2 7OF3 7OF4 7OF5 7OF6 7OF7 7OG4 7OI6 7OI7 7OI8 7OI9 7OIA 7OIB 7OIC 7OID 7OIE 7PD3 7PO4 7QH6 7QH7 7QI4 7QI5 7QI6 8ANY 8K2A 8K2B 8OIR 8OIT 8PK0 8QSJ 8QU5 8RRI 8XT0 8XT1 8XT2 8XT3	6ZM5 7A5K
Enriched GO Terms of Interacting Partners?		Heart Process Polarized Epithelial Cell Differentiation Regulation Of ATP-dependent Activity Neuron Projection Organization Cellular Component Assembly Acetylcholine Receptor Activator Activity Amyloid-beta Complex Regulation Of Plasma Membrane Bounded Cell Projection Organization PTB Domain Binding Regulation Of Extrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Regulation Of Growth Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Protein-containing Complex Organization Regulation Of Cell Projection Organization Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Protein Tetramerization Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Positive Regulation Of Endocytosis Growth Cone Filopodium Regulation Of Postsynapse Organization Protein-containing Complex Lipoprotein Particle Regulation Of Protein Localization To Nucleus Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Developmental Growth Involved In Morphogenesis Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Cell Growth Endothelin Receptor Signaling Pathway Involved In Heart Process GBD Domain Binding Storage Vacuole TEAD-YAP Complex Enterocyte Differentiation Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Transport Along Microtubule Positive Regulation Of Supramolecular Fiber Organization Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Apolipoprotein A-I Receptor Binding Neuropilin Signaling Pathway Mitochondrial Protein Quality Control Lateral Mesoderm Development	Mitochondrial Ribosome Mitochondrial Large Ribosomal Subunit Mitochondrial Translation Ribosome Translation Ribonucleoprotein Complex Mitochondrial Inner Membrane Structural Constituent Of Ribosome Protein Metabolic Process Macromolecule Biosynthetic Process Mitochondrion Macromolecule Metabolic Process Response To Glial Cell Derived Neurotrophic Factor Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
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