OXA1L and MRPL48

Number of citations of the paper that reports this interaction (PubMedID 20601428)
45

Data Source:
BioGRID (pull down)

		OXA1L	MRPL48
Description		OXA1L mitochondrial inner membrane insertase	mitochondrial ribosomal protein L48
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Mitochondrial Membrane Protein-containing Complex	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Large Ribosomal Subunit Ribosome Ribonucleoprotein Complex
	Molecular Function	Protein Binding Membrane Insertase Activity Protein Homodimerization Activity Mitochondrial Ribosome Binding	Protein Binding
	Biological Process	Aerobic Respiration Mitochondrial Translation Negative Regulation Of ATP-dependent Activity Protein Insertion Into Mitochondrial Inner Membrane From Matrix Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial Proton-transporting ATP Synthase Complex Assembly Protein Tetramerization Negative Regulation Of Oxidoreductase Activity Mitochondrial Protein Quality Control	Mitochondrial Translation
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Complex I biogenesis Mitochondrial ribosome-associated quality control	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		Intraocular pressure ( 30591961) Metabolite levels ( 23823483) Response to hepatitis B vaccine ( 29534301)	Dimensional psychopathology (Cognitive) ( 29496196) Major depressive disorder ( 29317602) Obesity-related traits ( 23251661)
Interacting Genes		6 interacting genes: CBLC MRPL20 MRPL28 MRPL48 MRPL49 MRPL51	4 interacting genes: APP EXOSC2 LSM8 OXA1L
Entrez ID		5018	51642
HPRD ID		03043	14767
Ensembl ID		ENSG00000155463	ENSG00000175581
Uniprot IDs		J3KNA0 Q15070 Q2M1J6	F5H702 F5H8D0 Q96GC5
PDB IDs		6ZM5 7A5K	3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5H 7A5I 7A5J 7A5K 7L08 7L20 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF2 7OF3 7OF4 7OF5 7OF6 7OF7 7OG4 7OI7 7OI8 7OI9 7OIA 7OIB 7OIC 7OID 7OIE 7PD3 7PO4 7QH7 7QI4 7QI5 7QI6 8ANY 8K2A 8K2B 8OIR 8OIT 8PK0 8QSJ 8QU5 8RRI 8XT0 8XT1 8XT2 8XT3
Enriched GO Terms of Interacting Partners?		Mitochondrial Ribosome Mitochondrial Large Ribosomal Subunit Mitochondrial Translation Ribosome Translation Ribonucleoprotein Complex Mitochondrial Inner Membrane Structural Constituent Of Ribosome Protein Metabolic Process Macromolecule Biosynthetic Process Mitochondrion Macromolecule Metabolic Process Response To Glial Cell Derived Neurotrophic Factor Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Regulation Of Spontaneous Synaptic Transmission Growth Cone Lamellipodium Axon Choice Point Recognition Collateral Sprouting In Absence Of Injury Protein Complex Oligomerization Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition NMDA Selective Glutamate Receptor Signaling Pathway Amylin Binding Regulation Of Synapse Structure Or Activity Endosome To Plasma Membrane Transport Vesicle Protein Tetramerization Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Toll Signaling Pathway Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Proton-transporting ATP Synthase Complex Assembly Mitochondrial Ribosome Binding Mitochondrial Proton-transporting ATP Synthase Complex Assembly Mitochondrial Protein Quality Control Protein Insertion Into Mitochondrial Inner Membrane From Matrix Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) 7S RNA Binding TRAMP-dependent TRNA Surveillance Pathway TRNA Surveillance Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Lsm2-8 Complex Heparan Sulfate Binding Signaling Receptor Activator Activity Negative Regulation Of Oxidoreductase Activity U4 SnRNA 3'-end Processing
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