TUFM and ATP6V1A

Number of citations of the paper that reports this interaction (PMID 11741979)
7

Data Source:
HPRD (in vitro)

		TUFM	ATP6V1A
Gene Name		Tu translation elongation factor, mitochondrial	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Membrane Mitochondrial Nucleoid Extracellular Vesicular Exosome	Mitochondrion Lysosomal Membrane Cytosol Plasma Membrane Integral Component Of Plasma Membrane Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Proton-transporting V-type ATPase, V1 Domain Extracellular Vesicular Exosome
	Molecular Function	Translation Elongation Factor Activity GTPase Activity GTP Binding Poly(A) RNA Binding	ATP Binding Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Translational Elongation Organelle Organization Mitochondrial Translation Mitochondrial Translational Elongation	Transport Cellular Iron Ion Homeostasis Insulin Receptor Signaling Pathway ATP Hydrolysis Coupled Proton Transport Transferrin Transport ATP Metabolic Process Interaction With Host Transmembrane Transport Phagosome Maturation
Pathways		Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation	Phagosomal maturation (early endosomal stage) Iron uptake and transport Latent infection of Homo sapiens with Mycobacterium tuberculosis Transferrin endocytosis and recycling Insulin receptor recycling Signaling by Insulin receptor
Drugs
Diseases
GWAS		Body mass index ( 20935630)	Prostate cancer ( 23535732)
Protein-Protein Interactions		7 interactors: ARL6IP1 ATP6V1A CMTM5 EXOSC6 FAM9B FUNDC1 MYH9	5 interactors: ANXA7 CDKN1A SMN1 TK1 TUFM
Entrez ID		7284	523
HPRD ID		03861	06120
Ensembl ID		ENSG00000178952	ENSG00000114573
Uniprot IDs		P49411	B7Z1R5 P38606
PDB IDs
Enriched GO Terms of Interacting Partners?			Fetal Process Involved In Parturition Digestive Tract Development Digestive System Development Skeletal Muscle Cell Proliferation Response To Glucocorticoid Response To Corticosteroid Response To Organic Cyclic Compound Response To Toxic Substance Intestinal Epithelial Cell Maturation Response To Cortisol Thymidine Metabolic Process Cellular Response To UV-B Deoxyribonucleoside Monophosphate Biosynthetic Process Response To Metal Ion Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Stress-induced Premature Senescence Cellular Water Homeostasis Mitotic Cell Cycle Arrest Response To UV-B Intestinal Epithelial Cell Development Response To Extracellular Stimulus Response To Inorganic Substance Parturition Regulation Of Protein Import Into Nucleus, Translocation Response To Steroid Hormone Intestinal Epithelial Cell Differentiation Epithelial Cell Maturation Response To Copper Ion Epithelial Cell Differentiation See more
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