TUFM and ATP6V1A

Number of citations of the paper that reports this interaction (PubMedID 11741979)
0

Data Source:
HPRD (in vitro)

		TUFM	ATP6V1A
Description		Tu translation elongation factor, mitochondrial	ATPase H+ transporting V1 subunit A
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Membrane Mitochondrial Nucleoid Extracellular Exosome	Golgi Membrane Vacuolar Proton-transporting V-type ATPase, V1 Domain Nucleoplasm Cytoplasm Lysosome Lysosomal Membrane Cytosol Plasma Membrane Microvillus Endosome Membrane Membrane Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Transport Vesicle Secretory Granule Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Proton-transporting V-type ATPase Complex Proton-transporting V-type ATPase, V1 Domain Extracellular Exosome Extrinsic Component Of Synaptic Vesicle Membrane ATPase Complex
	Molecular Function	Nucleotide Binding Magnesium Ion Binding RNA Binding Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding	Nucleotide Binding Protein Binding ATP Binding ATP Hydrolysis Activity Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Translation Translational Elongation Mitochondrial Translational Elongation	Monoatomic Ion Transport Intracellular Iron Ion Homeostasis Vacuolar Acidification Lysosomal Lumen Acidification Regulation Of Macroautophagy Cellular Response To Increased Oxygen Levels Homeostatic Process ATP Metabolic Process Endosomal Lumen Acidification Intracellular PH Reduction Golgi Lumen Acidification Synaptic Vesicle Lumen Acidification Proton Transmembrane Transport
Pathways		Mitochondrial translation elongation SARS-CoV-2 modulates autophagy	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy
Drugs		Zinc Guanosine-5'-Diphosphate Zinc acetate Zinc chloride Zinc sulfate, unspecified form	Alendronic acid Etidronic acid Tiludronic acid Bafilomycin A1 Bafilomycin B1
Diseases		Combined oxidative phosphorylation deficiency (COXPD)
GWAS		Alcohol consumption (drinks per week) ( 30643258) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body fat percentage ( 26833246) Body mass index ( 20935630) Brain morphology (MOSTest) ( 32665545) Crohn's disease ( 28067908) Educational attainment ( 25201988) Estimated glomerular filtration rate ( 31152163) Extremely high intelligence ( 29520040) Hip circumference adjusted for BMI ( 25673412) Inflammatory bowel disease ( 28067908) Intelligence ( 28530673) Lamb consumption ( 32066663) Walking pace ( 33128006)	Prostate cancer ( 23535732)
Interacting Genes		20 interacting genes: ARL6IP1 ASPH ATP6V1A CMTM5 DGAT2L6 EXOSC6 FAM9B FUNDC1 HMBOX1 LINC01554 MTIF3 MYH9 OGT PCAT1 PTEN RHBDD2 SYP TNFRSF10D XIAP ZDHHC15	7 interacting genes: ANXA7 CDC42 CDKN1A SMN1 TK1 TUFM UBC
Entrez ID		7284	523
HPRD ID		03861	06120
Ensembl ID		ENSG00000178952	ENSG00000114573
Uniprot IDs		A0A384ME17 P49411	P38606
PDB IDs		7A5G 7O9K	6WLZ 6WM2 6WM3 6WM4 7U4T 7UNF
Enriched GO Terms of Interacting Partners?
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