ATP6V1A and TUFM

Number of citations of the paper that reports this interaction (PubMedID 11741979)
0

Data Source:
HPRD (in vitro)

		ATP6V1A	TUFM
Description		ATPase H+ transporting V1 subunit A	Tu translation elongation factor, mitochondrial
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GO Annotations	Cellular Component	Golgi Membrane Vacuolar Proton-transporting V-type ATPase, V1 Domain Nucleoplasm Cytoplasm Lysosome Lysosomal Membrane Cytosol Plasma Membrane Microvillus Endosome Membrane Membrane Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Transport Vesicle Secretory Granule Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Proton-transporting V-type ATPase Complex Proton-transporting V-type ATPase, V1 Domain Extracellular Exosome Extrinsic Component Of Synaptic Vesicle Membrane ATPase Complex	Mitochondrion Mitochondrial Outer Membrane Membrane Mitochondrial Nucleoid Extracellular Exosome
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding ATP Hydrolysis Activity Proton-transporting ATPase Activity, Rotational Mechanism	Nucleotide Binding Magnesium Ion Binding RNA Binding Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Monoatomic Ion Transport Intracellular Iron Ion Homeostasis Vacuolar Acidification Lysosomal Lumen Acidification Regulation Of Macroautophagy Cellular Response To Increased Oxygen Levels Homeostatic Process ATP Metabolic Process Endosomal Lumen Acidification Intracellular PH Reduction Golgi Lumen Acidification Synaptic Vesicle Lumen Acidification Proton Transmembrane Transport	Translation Translational Elongation Mitochondrial Translational Elongation
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy	Mitochondrial translation elongation SARS-CoV-2 modulates autophagy
Drugs		Alendronic acid Etidronic acid Tiludronic acid Bafilomycin A1 Bafilomycin B1	Zinc Guanosine-5'-Diphosphate Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases			Combined oxidative phosphorylation deficiency (COXPD)
GWAS		Prostate cancer ( 23535732)	Alcohol consumption (drinks per week) ( 30643258) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body fat percentage ( 26833246) Body mass index ( 20935630) Brain morphology (MOSTest) ( 32665545) Crohn's disease ( 28067908) Educational attainment ( 25201988) Estimated glomerular filtration rate ( 31152163) Extremely high intelligence ( 29520040) Hip circumference adjusted for BMI ( 25673412) Inflammatory bowel disease ( 28067908) Intelligence ( 28530673) Lamb consumption ( 32066663) Walking pace ( 33128006)
Interacting Genes		7 interacting genes: ANXA7 CDC42 CDKN1A SMN1 TK1 TUFM UBC	20 interacting genes: ARL6IP1 ASPH ATP6V1A CMTM5 DGAT2L6 EXOSC6 FAM9B FUNDC1 HMBOX1 LINC01554 MTIF3 MYH9 OGT PCAT1 PTEN RHBDD2 SYP TNFRSF10D XIAP ZDHHC15
Entrez ID		523	7284
HPRD ID		06120	03861
Ensembl ID		ENSG00000114573	ENSG00000178952
Uniprot IDs		P38606	A0A384ME17 P49411
PDB IDs		6WLZ 6WM2 6WM3 6WM4 7U4T 7UNF	7A5G 7O9K
Enriched GO Terms of Interacting Partners?
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