SSX2B and TNPO3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SSX2B	TNPO3
Description		SSX family member 2B	transportin 3
Image
GO Annotations	Cellular Component	Nucleus	Nucleus Nuclear Envelope Annulate Lamellae Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity
	Biological Process	Regulation Of DNA-templated Transcription	Protein Import Into Nucleus Protein Transport
Pathways
Drugs
Diseases
GWAS			Diffuse cutaneous systemic sclerosis ( 29293537) Limited cutaneous systemic scleroderma ( 29293537) Platelet count ( 32888494) Plateletcrit ( 32888494) Primary biliary cholangitis ( 20639880) Primary biliary cirrhosis ( 22961000) Sjögren's syndrome ( 24097067) Systemic lupus erythematosus ( 18204446 32771030 28714469 26606652 26502338 24871463 23053960 18204098) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031) Systemic sclerosis ( 29293537 30247649 31672989 21750679) Systemic sclerosis (anti-centromere-positive) ( 29293537) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655) Ulcerative colitis ( 23128233 21297633)
Interacting Genes		6 interacting genes: FLACC1 FTSJ3 LRRC45 PHLDA2 TNPO3 TRAPPC2L	23 interacting genes: BLMH CAMK2B CAMK2D CAMK2G CEBPA CHMP3 CLPP ECI2 GCH1 ICA1L KRT75 KRTAP10-8 MEOX2 NME1 PPP1R1C PTEN RNF10 SMURF2 SRSF1 SSX2 SSX2B TRA2B USP7
Entrez ID		727837	23534
HPRD ID			18209
Ensembl ID		ENSG00000268447	ENSG00000064419
Uniprot IDs		Q16385 R9QTR3	B3KMX1 C9J7E5 E9PFH4 Q9Y5L0
PDB IDs		8HQY	4C0O 4C0P 4C0Q 4OL0 6GX9 8CMK
Enriched GO Terms of Interacting Partners?		Annulate Lamellae Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA (guanine) Methyltransferase Activity RNA 2'-O-methyltransferase Activity RRNA (uridine-2'-O-)-methyltransferase Activity RRNA Methyltransferase Activity Outer Dense Fiber	Calcium- And Calmodulin-dependent Protein Kinase Complex Identical Protein Binding Calcium/calmodulin-dependent Protein Kinase Activity Sarcoplasmic Reticulum Membrane Long-term Synaptic Potentiation Regulation Of Neuronal Synaptic Plasticity Regulation Of System Process Sarcoplasmic Reticulum Regulation Of Skeletal Muscle Adaptation Endocytic Vesicle Membrane Ubiquitin-specific Protease Binding Postsynaptic Density Regulation Of Protein Localization To Plasma Membrane Regulation Of Cellular Localization
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