TNPO3 and PPP1R1C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TNPO3	PPP1R1C
Description		transportin 3	protein phosphatase 1 regulatory inhibitor subunit 1C
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Annulate Lamellae Nucleoplasm Cytoplasm Cytosol	Cytoplasm
	Molecular Function	Protein Binding Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity	Protein Phosphatase Inhibitor Activity Protein Binding
	Biological Process	Protein Import Into Nucleus Protein Transport	Signal Transduction Intracellular Signal Transduction Cell Division
Pathways
Drugs
Diseases
GWAS		Diffuse cutaneous systemic sclerosis ( 29293537) Limited cutaneous systemic scleroderma ( 29293537) Platelet count ( 32888494) Plateletcrit ( 32888494) Primary biliary cholangitis ( 20639880) Primary biliary cirrhosis ( 22961000) Sjögren's syndrome ( 24097067) Systemic lupus erythematosus ( 18204446 32771030 28714469 26606652 26502338 24871463 23053960 18204098) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031) Systemic sclerosis ( 29293537 30247649 31672989 21750679) Systemic sclerosis (anti-centromere-positive) ( 29293537) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655) Ulcerative colitis ( 23128233 21297633)	Hip circumference adjusted for BMI ( 28552196) Systolic blood pressure ( 30578418)
Interacting Genes		23 interacting genes: BLMH CAMK2B CAMK2D CAMK2G CEBPA CHMP3 CLPP ECI2 GCH1 ICA1L KRT75 KRTAP10-8 MEOX2 NME1 PPP1R1C PTEN RNF10 SMURF2 SRSF1 SSX2 SSX2B TRA2B USP7	1 interacting genes: TNPO3
Entrez ID		23534	151242
HPRD ID		18209	15169
Ensembl ID		ENSG00000064419	ENSG00000150722
Uniprot IDs		B3KMX1 C9J7E5 E9PFH4 Q9Y5L0	Q8WVI7
PDB IDs		4C0O 4C0P 4C0Q 4OL0 6GX9 8CMK
Enriched GO Terms of Interacting Partners?		Calcium- And Calmodulin-dependent Protein Kinase Complex Identical Protein Binding Calcium/calmodulin-dependent Protein Kinase Activity Sarcoplasmic Reticulum Membrane Long-term Synaptic Potentiation Regulation Of Neuronal Synaptic Plasticity Regulation Of System Process Sarcoplasmic Reticulum Regulation Of Skeletal Muscle Adaptation Endocytic Vesicle Membrane Ubiquitin-specific Protease Binding Postsynaptic Density Regulation Of Protein Localization To Plasma Membrane Regulation Of Cellular Localization	Annulate Lamellae Nuclear Import Signal Receptor Activity
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