TNPO3 and SSX2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TNPO3	SSX2
Description		transportin 3	SSX family member 2
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Annulate Lamellae Nucleoplasm Cytoplasm Cytosol	Nucleus
	Molecular Function	Protein Binding Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity	Protein Binding
	Biological Process	Protein Import Into Nucleus Protein Transport	Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases			Synovial sarcoma
GWAS		Diffuse cutaneous systemic sclerosis ( 29293537) Limited cutaneous systemic scleroderma ( 29293537) Platelet count ( 32888494) Plateletcrit ( 32888494) Primary biliary cholangitis ( 20639880) Primary biliary cirrhosis ( 22961000) Sjögren's syndrome ( 24097067) Systemic lupus erythematosus ( 18204446 32771030 28714469 26606652 26502338 24871463 23053960 18204098) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031) Systemic sclerosis ( 29293537 30247649 31672989 21750679) Systemic sclerosis (anti-centromere-positive) ( 29293537) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655) Ulcerative colitis ( 23128233 21297633)
Interacting Genes		23 interacting genes: BLMH CAMK2B CAMK2D CAMK2G CEBPA CHMP3 CLPP ECI2 GCH1 ICA1L KRT75 KRTAP10-8 MEOX2 NME1 PPP1R1C PTEN RNF10 SMURF2 SRSF1 SSX2 SSX2B TRA2B USP7	17 interacting genes: AKAP9 BLZF1 FLACC1 FTSJ3 KRT40 LRRC45 MAGEC2 PHLDA2 RAB3IP RNF2 SSX2IP SYCE1 TAX1BP1 TNPO3 TRAPPC2L ZBED1 ZMIZ2
Entrez ID		23534	6757
HPRD ID		18209	02180
Ensembl ID		ENSG00000064419	ENSG00000241476
Uniprot IDs		B3KMX1 C9J7E5 E9PFH4 Q9Y5L0	Q16385 R9QTR3
PDB IDs		4C0O 4C0P 4C0Q 4OL0 6GX9 8CMK	8HQY
Enriched GO Terms of Interacting Partners?		Calcium- And Calmodulin-dependent Protein Kinase Complex Identical Protein Binding Calcium/calmodulin-dependent Protein Kinase Activity Sarcoplasmic Reticulum Membrane Long-term Synaptic Potentiation Regulation Of Neuronal Synaptic Plasticity Regulation Of System Process Sarcoplasmic Reticulum Regulation Of Skeletal Muscle Adaptation Endocytic Vesicle Membrane Ubiquitin-specific Protease Binding Postsynaptic Density Regulation Of Protein Localization To Plasma Membrane Regulation Of Cellular Localization	SUMO Ligase Activity
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