RNF208 and BUD31

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		RNF208	BUD31
Description		ring finger protein 208	BUD31 spliceosome associated protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol	Chromatin Nucleus Nucleoplasm Spliceosomal Complex Centrosome Microtubule Cytoskeleton U2-type Catalytic Step 2 Spliceosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Transcription Coactivator Activity Protein Binding Nuclear Receptor Binding
	Biological Process	Protein Ubiquitination Protein Autoubiquitination	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Positive Regulation Of DNA-templated Transcription
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Facial emotion recognition (sad faces) ( 28608620) Serum metabolite levels ( 23093944)
Interacting Genes		18 interacting genes: BUD31 CREB5 DAZAP2 GRB2 HOXA1 KRTAP15-1 KRTAP26-1 LITAF OXER1 PIN1 RNF38 RPIA SH3RF1 STAC TRIM32 UBQLN1 UBQLN2 USP54	25 interacting genes: ADCY7 APP ATP13A1 BEND5 CCT3 CEBPA CTNNBL1 ERGIC3 HLA-A HOXA1 HTR5A KRTAP10-3 KRTAP10-7 MARCHF6 MEOX2 MMP24 NPC1 PANX1 PICK1 RELB RNF208 SCAF1 SF1 TMEM94 TSPAN7
Entrez ID		727800	8896
HPRD ID			10351
Ensembl ID		ENSG00000212864	ENSG00000106245
Uniprot IDs		Q9H0X6	P41223
PDB IDs			4OED 4OH6 4OKB 5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM 7AAV 7ABF 7ABG 7ABI 7QTT 7W59 7W5A 7W5B 8C6J 8CH6 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 8Q7N 8QO9 8RO2 9FMD
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Regulation Of Protein Catabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Autophagosome Positive Regulation Of Metabolic Process Autophagosome Organization Autophagosome Assembly Positive Regulation Of ERAD Pathway Positive Regulation Of Proteasomal Protein Catabolic Process WW Domain Binding Regulation Of ERAD Pathway Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Macromolecule Metabolic Process Guanyl-nucleotide Exchange Factor Adaptor Activity Semicircular Canal Formation Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Cis-trans Isomerase Activity Ribose-5-phosphate Isomerase Activity Vacuole Organization Positive Regulation Of Interleukin-17-mediated Signaling Pathway Actin Ubiquitination Positive Regulation Of Chemokine (C-C Motif) Ligand 20 Production Regulation Of Proteolysis Regulation Of Macroautophagy Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Store-operated Calcium Channel Activity 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding Positive Regulation Of Protein Metabolic Process Regulation Of Autophagosome Assembly Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of RNA Metabolic Process Grb2-EGFR Complex Abducens Nerve Formation Optokinetic Behavior Cytoplasmic Side Of Late Endosome Membrane Protein Localization To Phagocytic Vesicle Regulation Of Vacuole Organization Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Catabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Protein Peptidyl-prolyl Isomerization Phosphothreonine Residue Binding Protein Polymerization Transcription Coactivator Activity D-ribose Metabolic Process
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