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DNAJC7 and UBE4B
Number of citations of the paper that reports this interaction (PMID
15189447
)
22
Data Source:
HPRD
(two hybrid)
DNAJC7
UBE4B
Gene Name
DnaJ (Hsp40) homolog, subfamily C, member 7
ubiquitination factor E4B
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytoskeleton
Membrane
Extracellular Vesicular Exosome
Ubiquitin Ligase Complex
Nucleus
Cytoplasm
Molecular Function
Protein Binding
Heat Shock Protein Binding
Ligase Activity
Enzyme Binding
Ubiquitin-ubiquitin Ligase Activity
Biological Process
Protein Folding
Chaperone Cofactor-dependent Protein Refolding
Granzyme-mediated Apoptotic Signaling Pathway
Response To UV
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS
Hepatocellular carcinoma (
20676096
)
Protein-Protein Interactions
14 interactors:
DISC1
HSP90AA1
HSPA1A
HSPA8
HUS1
MKNK1
NF1
RAD1
RAD9A
SMAD2
SMAD9
SMURF1
TP53
UBE4B
15 interactors:
ATXN3
CASP3
CASP6
CASP7
CDKN2A
DNAJC7
FEZ1
GZMB
HGS
TP53
TRIP12
UBE2D2
UBE2D3
VAV2
VCP
Entrez ID
7266
10277
HPRD ID
07046
11659
Ensembl ID
ENSG00000168259
ENSG00000130939
Uniprot IDs
Q99615
O95155
PDB IDs
2KRE
3L1X
3L1Z
Enriched GO Terms of Interacting Partners
?
Response To Abiotic Stimulus
Cellular Response To Stimulus
Cellular Response To Ionizing Radiation
Response To Radiation
Protein Refolding
Response To Stimulus
Regulation Of Cellular Response To Heat
Cellular Response To Radiation
Transforming Growth Factor Beta Receptor Signaling Pathway
Response To Ionizing Radiation
DNA Damage Checkpoint
Response To Stress
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Regulation Of Neuroblast Proliferation
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Response To Heat
Cell Cycle Checkpoint
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Cellular Response To Stress
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Response To Organic Substance
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Neural Precursor Cell Proliferation
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Response To Light Stimulus
Regulation Of Stem Cell Proliferation
Response To Heat
Apoptotic Signaling Pathway
Brain Development
Response To UV
Anatomical Structure Development
Response To Unfolded Protein
Head Development
Regulation Of Cellular Process
Cellular Macromolecule Catabolic Process
Negative Regulation Of Neuroblast Proliferation
Mitotic Cell Cycle Checkpoint
Negative Regulation Of Cell Cycle
Cell Surface Receptor Signaling Pathway
Regulation Of Cell Cycle
Cellular Metabolic Process
Nervous System Development
Regulation Of Cell Differentiation
Regulation Of Cellular Response To Growth Factor Stimulus
Negative Regulation Of Stem Cell Proliferation
Developmental Process
Apoptotic Process
Programmed Cell Death
Cell Death
Death
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Proteolysis
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Protein Processing
Activation Of Cysteine-type Endopeptidase Activity
Zymogen Activation
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity
Cellular Response To Stress
Positive Regulation Of Endopeptidase Activity
Apoptotic Signaling Pathway
Positive Regulation Of Peptidase Activity
Cellular Response To Stimulus
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Cell Aging
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Glial Cell Apoptotic Process
Regulation Of Cysteine-type Endopeptidase Activity
Cellular Response To DNA Damage Stimulus
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Cellular Macromolecule Catabolic Process
Regulation Of Apoptotic DNA Fragmentation
Ubiquitin-dependent Protein Catabolic Process
Apoptotic Mitochondrial Changes
Modification-dependent Protein Catabolic Process
Regulation Of Apoptotic Process
Execution Phase Of Apoptosis
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Regulation Of Cell Death
Cellular Response To Growth Factor Stimulus
Negative Regulation Of Macroautophagy
Protein Ubiquitination
DNA Repair
Response To Growth Factor
Protein Modification By Small Protein Conjugation
DNA Metabolic Process
Protein Catabolic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C
Positive Regulation Of Proteolysis
Response To Abiotic Stimulus
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Cellular Response To Oxygen Levels
Tagcloud
?
aberrantly
amplified
archived
battery
bel
caspase3
cleaved
colony
contradictory
hcc
hep1
hep3b
hepatocellular
hepatocyte
hepg2
huh7
immunohistochjemical
inc
lo2
oncogene
periodicals
resection
sk
smmc
speculated
ubiquitination
undergone
wiley
Tagcloud (Difference)
?
aberrantly
amplified
archived
battery
bel
caspase3
cleaved
colony
contradictory
hcc
hep1
hep3b
hepatocellular
hepatocyte
hepg2
huh7
immunohistochjemical
inc
lo2
oncogene
periodicals
resection
sk
smmc
speculated
ubiquitination
undergone
wiley
Tagcloud (Intersection)
?