TSPY1 and EEF1A2

Number of citations of the paper that reports this interaction (PubMedID 18649364)
0

Data Source:
HPRD (in vitro)

		TSPY1	EEF1A2
Description		testis specific protein Y-linked 1	eukaryotic translation elongation factor 1 alpha 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Eukaryotic Translation Elongation Factor 1 Complex Membrane Synapse Cytoplasmic Side Of Lysosomal Membrane
	Molecular Function	Chromatin Binding Protein Binding Histone Binding	Nucleotide Binding Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding Translation Factor Activity, RNA Binding Hydrolase Activity Protein Kinase Binding Metal Ion Binding
	Biological Process	Nucleosome Assembly Spermatogenesis Gonadal Mesoderm Development Sex Differentiation Cell Differentiation	Translation Translational Elongation Positive Regulation Of Apoptotic Process Positive Regulation Of Lipid Kinase Activity Regulation Of Chaperone-mediated Autophagy
Pathways			Eukaryotic Translation Elongation
Drugs			Plitidepsin
Diseases		46,XY disorders of sex development (Disorders of gonadal development), including: Gonadal agenesis; Complete and partial gonadal dysgenesis; Testis regression; Ovotesticular DSD
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Prostate cancer ( 23535732) Serum metabolite levels ( 33031748)
Interacting Genes		5 interacting genes: CSNK2A1 EEF1A1 EEF1A2 H2AC20 H2BC21	12 interacting genes: CHRM4 ERG HUNK LINC00941 MAPK6 PKNOX1 SMN1 STK11 SUMO2 TSPY1 TTLL12 UBE3A
Entrez ID		7258	1917
HPRD ID		11852	04265
Ensembl ID		ENSG00000258992	ENSG00000101210
Uniprot IDs		Q01534	Q05639
PDB IDs			3C5J 8B6Z
Enriched GO Terms of Interacting Partners?		Eukaryotic Translation Elongation Factor 1 Complex Regulation Of Chaperone-mediated Autophagy Cytoplasmic Side Of Lysosomal Membrane Translation Elongation Factor Activity Regulation Of Protein Catabolic Process Regulation Of Autophagy Translational Elongation Structural Constituent Of Chromatin Positive Regulation Of Lipid Kinase Activity Nucleosome Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Lipid Kinase Activity Positive Regulation Of Aggrephagy Aggrephagy Double-strand Break Repair Via Classical Nonhomologous End Joining Protein Targeting To Vacuole Involved In Autophagy Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA GTPase Activity Translation Kinase Activator Activity Host-mediated Perturbation Of Viral Genome Replication Host-mediated Activation Of Viral Genome Replication Protein Heterodimerization Activity GTP Binding
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