ANXA6

Name	annexin A6
Structure
Interactors	19 interactors: A2M CDC73 CEBPA CR2 ERBB2 IL16 LINC00632 LINC01554 MLH1 MTNR1B OGT PDE4B RASA1 RHOU S100A1 S100B SMURF1 SNCA TPD52
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Lysosomal Membrane Plasma Membrane Focal Adhesion Vesicle Membrane Membrane Extracellular Matrix Late Endosome Membrane Melanosome Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Phosphatidylserine Binding Calcium Ion Binding Protein Binding GTP Binding Calcium-dependent Phospholipid Binding Lipid Binding Ligand-gated Monoatomic Ion Channel Activity Cholesterol Binding Identical Protein Binding Calcium-dependent Protein Binding
	Biological Process	Calcium Ion Transport Regulation Of Muscle Contraction Monoatomic Ion Transmembrane Transport Negative Regulation Of Sequestering Of Calcium Ion Mitochondrial Calcium Ion Homeostasis Apoptotic Signaling Pathway
Pathways	Smooth Muscle Contraction
GWAS	Crohn's disease ( 28067908 ) Inflammatory bowel disease ( 28067908 ) Inflammatory skin disease ( 25574825 ) Lymphocyte count ( 32888494 ) Psoriasis ( 25574825 25903422 ) Psoriatic arthritis ( 26626624 )
Entrez ID	309
HPRD ID	00231
Ensembl ID	ENSG00000197043
Uniprot IDs	A0A0S2Z2Z6 A0A0S2Z377 P08133
PDB IDs	1M9I
GO Terms Enriched among Interactors ?	Regulation Of Multicellular Organismal Process Regulation Of Immune System Process Positive Regulation Of Multicellular Organismal Process Signaling Receptor Binding Calcium-dependent Protein Binding Cellular Developmental Process Negative Regulation Of Complement Activation Signal Transduction Regulation Of Developmental Process Cellular Response To Epinephrine Stimulus S100 Protein Binding Response To Epinephrine Regulation Of Cell Morphogenesis Regulation Of Anatomical Structure Morphogenesis Regulation Of Complement Activation Leukocyte Activation Regulation Of Cell Shape Developmental Process Regulation Of Cell Activation Regulation Of Signal Transduction Cell Activation Enzyme Binding Regulation Of Ubiquitin-dependent Protein Catabolic Process Cell Surface Receptor Signaling Pathway RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Protein Homodimerization Activity Positive Regulation Of Inflammatory Response Regulation Of Programmed Cell Death Regulation Of Biological Quality Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Negative Regulation Of Neuron Apoptotic Process Tau Protein Binding Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Engulfment Of Target By Autophagosome Growth Factor Binding B Cell Activation Regulation Of Humoral Immune Response Positive Regulation Of Proteolysis Carbohydrate Homeostasis Glucose Homeostasis Response To Lipid Lymphocyte Activation Negative Regulation Of Complement Activation, Lectin Pathway