TNXB and BANP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid, two hybrid)

		TNXB	BANP
Description		tenascin XB	BTG3 associated nuclear protein
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix Extracellular Exosome Tenascin Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Body Nuclear Speck
	Molecular Function	Integrin Binding Extracellular Matrix Structural Constituent Protein Binding Collagen Binding Heparin Binding Collagen Fibril Binding	DNA Binding RNA Binding Protein Binding Identical Protein Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Triglyceride Metabolic Process Cell Adhesion Cell-matrix Adhesion Positive Regulation Of Cell Population Proliferation Positive Regulation Of Epithelial To Mesenchymal Transition Actin Cytoskeleton Organization Regulation Of Cell Adhesion Extracellular Matrix Organization Collagen Fibril Organization Regulation Of Cell Migration Neuron Projection Development Collagen Metabolic Process Regulation Of Cell Differentiation Regulation Of JNK Cascade Elastic Fiber Assembly Cell-cell Adhesion Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Collagen Fibril Organization Positive Regulation Of Cell Fate Determination	Chromatin Organization
Pathways		ECM proteoglycans	Regulation of TP53 Activity through Association with Co-factors Degradation of CDH1
Drugs
Diseases		Ehlers-Danlos syndrome (EDS), including: EDS classical type (EDS1/2); EDS hypermobility type (EDS3); EDS vascular type (EDS4); EDS kyphoscoliosis type (EDS6); EDS arthrochalasia type (EDS7A/7B); EDS dermatospraxis type (EDS7C); EDS autosomal recessive cardiac valvular form (EDSCV); EDS musculocontractural type (EDSMC); EDS progeroid form (EDSP); Tenascin-X deficiency (TNXD); Brittle cornea syndrome (EDS6B); EDS-like spondylocheiro dysplasia (SCD-EDS)
GWAS		A body shape index ( 34021172) Age-related macular degeneration ( 22694956) Alzheimer's disease ( 30636644) Asthma ( 31619474) Atopic dermatitis ( 23886662) Autism spectrum disorder or schizophrenia ( 28540026) Automobile speeding propensity ( 30643258) Coronary artery disease ( 32469254) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Eosinophil count ( 27863252) Femur bone mineral density x serum urate levels interaction ( 34046847) Hemoglobin levels ( 32327693) Hip circumference adjusted for BMI ( 34021172) HIV-1 control ( 20041166) Inflammatory bowel disease ( 28067908) Intraocular pressure ( 30054594 29617998) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Mean corpuscular volume ( 27863252 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Neutrophil count ( 32888494) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Platelet distribution width ( 32888494) Prostate cancer ( 23535732) Refractive error ( 32231278) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Schizophrenia ( 30285260) Shingles ( 28928442) Squamous cell lung carcinoma ( 28604730) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus ( 26316170 26502338 28714469 21408207) Systolic blood pressure ( 28739976) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Type 1 diabetes and autoimmune thyroid diseases ( 25936594) Ulcerative colitis ( 28067908) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White blood cell count ( 32888494 27863252)	Apolipoprotein A1 levels ( 32203549) Central corneal thickness ( 20719862 28171582) Corneal structure ( 23291589) HDL cholesterol levels ( 32203549) Intraocular pressure ( 29235454) Keratoconus ( 33649486) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Systolic blood pressure ( 30224653) Triglyceride levels ( 32203549)
Interacting Genes		6 interacting genes: BANP CEACAM6 POU6F2 TGM7 VEGFA VEGFB	193 interacting genes: ABLIM3 ADAM15 AFG1L ALAS2 ANAPC11 ANKRD55 ANTKMT ARID5A ATF2 ATXN7L2 BAG5 BICRAL BLZF1 BOC BTG3 C1orf94 C1QTNF2 C22orf15 C22orf39 C3orf36 CAMK2D CBX8 CCDC26 CCDC74B CDC7 CDSN CDX4 CEP76 CFAP206 CHRDL2 COL10A1 CRX CSNK2B CTSZ CYTOR DCDC2B DLX3 DNAJA4 ENKD1 EPHA10 ESM1 FAM117B FAM120C FAM217B FAM222B FAM90A1 FARS2 FHL2 FHL5 FLOT1 FOXM1 FOXR1 GARIN6 GAS2L2 GFM2 GOLGA6L9 HAPLN2 HEYL HHIPL1 HIVEP1 HMGB3P1 HNRNPLL HSFY1 IDO2 IGF1 IGFN1 INO80B ISCU KCTD9 KHDC4 KLF15 KRTAP8-1 L3MBTL3 LAP3 LENG1 LGALS14 LGALS4 LHX4 LHX8 LIN54 LINC01547 LMO1 LMO2 LMO3 LMO4 LRIF1 LSM2 MAP2K1 MAPK1 MAX MDFI MEOX1 MEOX2 MIR4435-2HG MRPL28 MRRF MSRB3 MTERF4 MVP NEDD9 NFYA NMNAT1 NOTO NRIP2 PANX2 PARD6B PAX6 PHF21A PHF21B PID1 PIH1D2 PIK3C2G PIM1 PML PNRC2 POGZ POLDIP3 POLR2L POU6F2 PPIB PPIC PPIF PRDM6 PRKAB2 PRKCH PRPF39 PRR20A PRR20B PRR20C PRR20D PRR20E PRR23B PRR34 PSMD9 PSORS1C2 RAB3IP RAD54L2 RBM39 RBPMS REL RELA RHNO1 RHOH RHOQ RIDA RIMS3 RPP25 RYBP SAPCD1 SCN5A SH3RF2 SLC16A3 SLC19A4P SNAPIN SNRPB SNX5 SP2 SP4 SPACA6 SPANXN2 SPMIP2 SRARP STK38 STOX1 TAF6 TERF2 TERF2IP TNXB TOX TOX4 TP53 TRAF2 TRAF4 TRIM35 TROAP TTC23 UBAP2 UBE2I VEZF1 XAGE1B YJU2 ZBTB4 ZC2HC1C ZMIZ2 ZMYM6 ZNF410 ZNF438 ZNF471 ZNF474 ZNF488 ZNF512B ZNF580 ZNF581
Entrez ID		7148	54971
HPRD ID		02993	16538
Ensembl ID		ENSG00000168477	ENSG00000172530
Uniprot IDs		A0A3B3ISX9 O95680 O95681 P22105 Q6IPK3 Q9Y464	A0A0S2Z5C2 A0A0S2Z5M2 A0A804HKG3 B3KM38 B4DE54 Q8N9N5
PDB IDs		2CUH 2CUI 2CUM	7YUG 7YUK 8HTX 8YZT
Enriched GO Terms of Interacting Partners?		Vascular Endothelial Growth Factor Receptor Binding Vascular Endothelial Growth Factor Receptor 1 Binding Positive Regulation Of Mast Cell Chemotaxis Regulation Of Mast Cell Chemotaxis Positive Regulation Of Heterotypic Cell-cell Adhesion Regulation Of Vascular Wound Healing Receptor Ligand Activity Regulation Of Endothelial Cell Proliferation Positive Regulation Of Leukocyte Migration Regulation Of Establishment Of Endothelial Barrier Vascular Endothelial Growth Factor Signaling Pathway Induction Of Positive Chemotaxis Positive Regulation Of Vascular Permeability Positive Regulation Of Cell Motility Positive Regulation Of Cell Migration Positive Regulation Of Locomotion Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Positive Chemotaxis Negative Regulation Of MiRNA Transcription Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Leukocyte Migration Chemoattractant Activity Positive Regulation Of Protein Phosphorylation Vascular Endothelial Growth Factor Receptor Signaling Pathway Sprouting Angiogenesis Positive Regulation Of Phosphorylation Regulation Of Endothelial Cell Differentiation Vascular Process In Circulatory System Positive Regulation Of DNA Biosynthetic Process Positive Chemotaxis Regulation Of ERK1 And ERK2 Cascade Regulation Of Vascular Permeability Identical Protein Binding Negative Regulation Of Apoptotic Process Vasodilation Positive Regulation Of Phosphate Metabolic Process Regulation Of Morphogenesis Of A Branching Structure Response To Decreased Oxygen Levels Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Response To Hypoxia Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Fat Cell Differentiation Regulation Of Angiogenesis Circulatory System Process Negative Regulation Of Programmed Cell Death Regulation Of Vasculature Development Positive Regulation Of Cell Population Proliferation Response To Oxygen Levels Positive Regulation Of Cell-matrix Adhesion	Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Protein Binding Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Chromatin Positive Regulation Of Macromolecule Metabolic Process Nucleus DNA Binding Positive Regulation Of Biosynthetic Process DNA-binding Transcription Factor Activity Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Nucleoplasm RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Binding Negative Regulation Of Macromolecule Metabolic Process Zinc Ion Binding Sequence-specific Double-stranded DNA Binding Cyclosporin A Binding Negative Regulation Of DNA Recombination At Telomere Positive Regulation Of Kinase Activity Negative Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Negative Regulation Of RNA Metabolic Process Protein Kinase Binding Regulation Of Kinase Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of Cyclin-dependent Protein Kinase Activity
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