TCF19 and DNAJA3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TCF19	DNAJA3
Gene Name		transcription factor 19	DnaJ (Hsp40) homolog, subfamily A, member 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Actin Filament IkappaB Kinase Complex Extrinsic Component Of Plasma Membrane Cell Junction Neuromuscular Junction I-kappaB/NF-kappaB Complex Mitochondrial Nucleoid Intracellular Membrane-bounded Organelle Postsynaptic Membrane
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Zinc Ion Binding	Small GTPase Regulator Activity Interferon-gamma Receptor Binding Protein Binding ATP Binding Transcription Factor Binding Protein Kinase Binding Hsp70 Protein Binding Receptor Tyrosine Kinase Binding Metal Ion Binding NF-kappaB Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Cell Proliferation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Mitochondrial DNA Replication Protein Folding Negative Regulation Of Protein Kinase Activity Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation-induced Cell Death Of T Cells Mitochondrion Organization Small GTPase Mediated Signal Transduction Neuromuscular Junction Development Cell Aging Negative Regulation Of Cell Proliferation Response To Heat Positive Regulation Of Protein Ubiquitination Negative Regulation Of NF-kappaB Transcription Factor Activity T Cell Differentiation In Thymus Response To Interferon-gamma Protein Refolding Positive Regulation Of T Cell Proliferation Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Catalytic Activity Protein Stabilization Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Skeletal Muscle Acetylcholine-gated Channel Clustering
Pathways
Drugs
Diseases
GWAS		Chronic hepatitis B infection ( 23760081) Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN) ( 21912425)
Protein-Protein Interactions		5 interactors: APP DNAJA3 GOLGA2 LZTR1 UBE3A	38 interactors: ALS2CR11 ATXN1 BRCA1 CARM1 COIL FAM131C FAM214B FOSL2 FRMD6 GCC1 GFI1B GRB2 HSPA1A HSPA8 HSPA9 IFNGR2 INPP5J JAK2 KDM1A KRAS MET MYO15B NFKBIA NFKBIB NOC4L NTRK1 OSGIN1 PRMT6 RAD51 RASA1 RELA RNF34 SMAD9 STK16 TCF19 USP7 VHL ZBTB22
Entrez ID		6941	9093
HPRD ID		15986	09758
Ensembl ID		ENSG00000137310	ENSG00000103423
Uniprot IDs		D2IYK5 Q9Y242	B3KM81 E7ES32 Q53G26 Q59E88 Q96EY1
PDB IDs			2CTT 2DN9
Enriched GO Terms of Interacting Partners?		Neuromuscular Junction Development Sperm Entry Regulation Of Proteolysis Regulation Of Protein Binding Positive Regulation Of Peptidase Activity Synaptic Growth At Neuromuscular Junction Synapse Organization Collateral Sprouting In Absence Of Injury Intracellular Receptor Signaling Pathway Regulation Of Protein Ubiquitination Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Binding Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Axon Choice Point Recognition Activation-induced Cell Death Of T Cells Developmental Growth Positive Regulation Of Proteolysis Neuron Remodeling Skeletal Muscle Acetylcholine-gated Channel Clustering Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Endopeptidase Activity Mitochondrial DNA Replication Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Peptidase Activity Posttranscriptional Regulation Of Gene Expression T Cell Apoptotic Process Cellular Copper Ion Homeostasis Regulation Of Transcription From RNA Polymerase II Promoter Growth Protein Refolding Mitochondrial DNA Metabolic Process Prostate Gland Growth Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Response To Interferon-gamma Copper Ion Homeostasis Suckling Behavior Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of RNA Metabolic Process Postsynaptic Membrane Organization Neuron Maturation	Response To Abiotic Stimulus Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Apoptotic Process Regulation Of RNA Metabolic Process Regulation Of Cell Death Regulation Of Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription, DNA-templated Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Apoptotic Process Response To Organic Substance Response To Organonitrogen Compound Response To Stress Regulation Of Signal Transduction Intracellular Receptor Signaling Pathway Regulation Of Cellular Process Cellular Response To Stress Response To External Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Cellular Response To Organic Substance Viral Process Positive Regulation Of NF-kappaB Transcription Factor Activity Transcription, DNA-templated Regulation Of Signaling RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Histone H3-R2 Methylation Response To Organic Cyclic Compound Response To Radiation Regulation Of Histone H3-K4 Methylation Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Proliferation Cellular Response To Organonitrogen Compound Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Cell Differentiation Negative Regulation Of Histone H3-K4 Methylation Cellular Response To Stimulus Response To Temperature Stimulus
Tagcloud ?		2lomb aetiology atad1 consortium covering dimensionality ensembles epistasis epistatic governed locate muc21 muc22 mucin multifactor omnibus outperforms permutation psors1c1 purely scenarios snp snps t1d tractable trust uk wellcome wtccc	acted adenocarcinoma allylamino causing cochaperone colony concluded conversely counteracting counterparts demethoxy differently egfr enhancing geldanamycin hsp70 hsp90 interacted inversely isoforms oncogenic orthotropic proteasomal restored subcutaneous tid1 ubiquitinylation xenograft
Tagcloud (Difference) ?		2lomb aetiology atad1 consortium covering dimensionality ensembles epistasis epistatic governed locate muc21 muc22 mucin multifactor omnibus outperforms permutation psors1c1 purely scenarios snp snps t1d tractable trust uk wellcome wtccc	acted adenocarcinoma allylamino causing cochaperone colony concluded conversely counteracting counterparts demethoxy differently egfr enhancing geldanamycin hsp70 hsp90 interacted inversely isoforms oncogenic orthotropic proteasomal restored subcutaneous tid1 ubiquitinylation xenograft
Tagcloud (Intersection) ?