RALGAPA1

Description		Ral GTPase activating protein catalytic subunit alpha 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	GTPase Activator Activity Protein Heterodimerization Activity
	Biological Process	Regulation Of Small GTPase Mediated Signal Transduction Activation Of GTPase Activity
Pathways		RHOH GTPase cycle
Drugs
Diseases
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Liver enzyme levels (alkaline phosphatase) ( 33972514) Monocyte count ( 32888494) Red blood cell count ( 32888494)
Novel Interacting Genes		2 novel interacting genes: ATP6V1A SRP54
Interacting Genes		2 interacting genes: ERBB3 TCF3
Entrez ID		253959
HPRD ID		12324
Ensembl ID		ENSG00000174373
Uniprot IDs		A0A1B0GUI1 A0A7P0TAR5 H0YJB5 Q6GYQ0
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleotide Binding ATPase Complex Proton-transporting V-type ATPase, V1 Domain Apical Plasma Membrane Extrinsic Component Of Synaptic Vesicle Membrane Proton-transporting Two-sector ATPase Complex Golgi Lumen Acidification Vacuolar Proton-transporting V-type ATPase, V1 Domain Endosomal Lumen Acidification Cellular Response To Increased Oxygen Levels Regulation Of Motor Neuron Apoptotic Process Positive Regulation Of Cardiac Muscle Tissue Development ErbB-3 Class Receptor Binding ERBB3:ERBB2 Complex Negative Regulation Of Motor Neuron Apoptotic Process Neuregulin Receptor Activity Motor Neuron Apoptotic Process ERBB2-ERBB3 Signaling Pathway Schwann Cell Differentiation ERBB3 Signaling Pathway Protein Tyrosine Kinase Activator Activity Neuregulin Binding Endocardial Cushion Development Regulation Of Cardiac Muscle Tissue Development Protein Heterodimerization Activity Leukocyte Differentiation Signal Recognition Particle Cotranslational Protein Targeting To Membrane Exocrine Pancreas Development Endoplasmic Reticulum Signal Peptide Binding Signal Recognition Particle, Endoplasmic Reticulum Targeting SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation 7S RNA Binding SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition SRP-dependent Cotranslational Protein Targeting To Membrane Vitamin D Response Element Binding B Cell Lineage Commitment Immunoglobulin V(D)J Recombination Mitogen-activated Protein Kinase Kinase Kinase Binding Synaptic Vesicle Lumen Acidification Proton-transporting V-type ATPase Complex Schwann Cell Development Positive Regulation Of Calcineurin-NFAT Signaling Cascade V(D)J Recombination Positive Regulation Of Striated Muscle Tissue Development ERBB2 Signaling Pathway Proton-transporting ATPase Activity, Rotational Mechanism Lysosomal Lumen Acidification Peripheral Nervous System Development Granulocyte Differentiation
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