SULT1A1

Gene Name		sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
Image
Gene Ontology Annotations	Cellular Component	Cytosol
	Molecular Function	Aryl Sulfotransferase Activity Sulfotransferase Activity Flavonol 3-sulfotransferase Activity Steroid Sulfotransferase Activity
	Biological Process	Catecholamine Metabolic Process Xenobiotic Metabolic Process Estrogen Metabolic Process Amine Metabolic Process Flavonoid Metabolic Process Small Molecule Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective UGT1A4 causes hyperbilirubinemia Metabolic disorders of biological oxidation enzymes Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Cytosolic sulfonation of small molecules Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GGT1 causes Glutathionuria (GLUTH) Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs		Adenosine-3\'-5\'-Diphosphate P-Nitrophenol
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Inflammatory bowel disease (early onset) ( 19915574)
Protein-protein Interactions		1 interactors: SULT2B1
Entrez ID		6817
HPRD ID		01372
Ensembl ID		ENSG00000196502
Uniprot IDs		P50225
PDB IDs		1LS6 1Z28 2D06 3QVU 3QVV 3U3J 3U3K 3U3M 3U3O 3U3R 4GRA
Enriched GO Terms of Interacting Partners?		Sulfate Assimilation 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Response To Xenobiotic Stimulus Purine Nucleoside Metabolic Process Steroid Metabolic Process Ribonucleotide Metabolic Process Nucleoside Metabolic Process Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Sulfur Compound Metabolic Process Nucleotide Metabolic Process
Tagcloud ?