STYX and CARHSP1

Number of citations of the paper that reports this interaction (PubMedID 11842224)
37

Data Source:
HPRD (in vivo)

		STYX	CARHSP1
Description		serine/threonine/tyrosine interacting protein	calcium regulated heat stable protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Cytoplasmic Exosome (RNase Complex) P-body Cytoplasm Cytosol P Granule
	Molecular Function	Pseudophosphatase Activity Protein Binding F-box Domain Binding	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Phosphatase Binding
	Biological Process	Negative Regulation Of Protein Binding Negative Regulation Of SCF-dependent Proteasomal Ubiquitin-dependent Catabolic Process Regulation Of ERK1 And ERK2 Cascade	Intracellular Signal Transduction Regulation Of MRNA Stability
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)	Alanine aminotransferase levels ( 33339817) Intracranial aneurysm ( 29531279)
Interacting Genes		24 interacting genes: AATK CARHSP1 EGFR EPHA2 EPHA3 EPHA7 EPHB6 ERBB2 ERBB3 ERBB4 FBXO7 FBXW7 IGF1R INSR INSRR KDR KIT LMTK2 MAPK1 MUSK PTK7 ROR1 ROR2 TEK	26 interacting genes: AKAP8L AKT1 CDC42 CYSRT1 DOCK8 GORASP2 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP6-3 MID2 NBPF19 NOTCH2NLA PIAS3 PIN1 PNMA1 PPP2R1A RPS6KA1 SGK1 SMN1 SRPK2 STC2 STYX TK1 TRAF1 TSC22D1
Entrez ID		6815	23589
HPRD ID		10258	08515
Ensembl ID		ENSG00000198252	ENSG00000153048
Uniprot IDs		Q8WUJ0	Q9Y2V2
PDB IDs		2R0B	3AQQ
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Kinase Activity Protein Tyrosine Kinase Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Kinase Activity Receptor Complex Enzyme-linked Receptor Protein Signaling Pathway ATP Binding Nucleotide Binding Transferase Activity Cell Surface Receptor Signaling Pathway Regulation Of MAPK Cascade Phosphorylation Protein Phosphorylation Growth Factor Binding ERBB2 Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of MAPK Cascade Protein Autophosphorylation Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Insulin Receptor Activity Signal Transduction Ephrin Receptor Activity Regulation Of ERK1 And ERK2 Cascade Regulation Of Intracellular Signal Transduction Positive Regulation Of Phosphate Metabolic Process Peptidyl-tyrosine Phosphorylation Animal Organ Development Insulin Receptor Complex Coreceptor Activity Positive Regulation Of Protein Phosphorylation Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Modification Process Basal Plasma Membrane Positive Regulation Of Cell Migration Regulation Of Protein Phosphorylation Positive Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Regulation Of Locomotion ERBB Signaling Pathway Regulation Of Phosphorylation Regulation Of Developmental Process Phosphate-containing Compound Metabolic Process Plasma Membrane Regulation Of Protein Modification Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling	Protein Serine/threonine/tyrosine Kinase Activity Regulation Of Signal Transduction Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Leading Edge Membrane Thioesterase Binding Intermediate Filament Intracellular Signal Transduction Regulation Of Cell Communication Glutamatergic Synapse Regulation Of Signaling Identical Protein Binding Regulation Of Growth Keratin Filament Nuclear Speck
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