SSX1 and MAGEC2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SSX1	MAGEC2
Description		SSX family member 1	MAGE family member C2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Cilium Motile Cilium Sperm Flagellum Cell Projection	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Transcription Corepressor Activity Protein Binding	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Spermatogenesis	Negative Regulation Of Transcription By RNA Polymerase II Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity
Pathways
Drugs
Diseases		Synovial sarcoma
GWAS			Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Non-response to bupropion and depression ( 27622933)
Interacting Genes		5 interacting genes: CDCA7L FUBP3 LHX4 MAGEC2 MTURN	15 interacting genes: MDM2 MNAT1 P4HA3 PBX3 PCGF6 RBX1 RNF166 SSX1 SSX2 TAF9 TRAF4 TRIM28 TRIM8 UBR3 ZMYND11
Entrez ID		6756	51438
HPRD ID		02428	06632
Ensembl ID		ENSG00000126752	ENSG00000046774
Uniprot IDs		Q16384	Q9UBF1
PDB IDs		8HR1
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Medial Motor Column Neuron Differentiation Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Metabolic Process Intracellular MRNA Localization Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Megakaryocyte Differentiation	Zinc Ion Binding Ubiquitin Protein Ligase Activity NEDD8 Ligase Activity Regulation Of Primary Metabolic Process Ubiquitin-dependent Protein Catabolic Process Regulation Of DNA-templated Transcription Modification-dependent Protein Catabolic Process Regulation Of RNA Biosynthetic Process Negative Regulation Of Signal Transduction By P53 Class Mediator Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of RNA Metabolic Process Protein Modification By Small Protein Conjugation Proteolysis Involved In Protein Catabolic Process Regulation Of Macromolecule Metabolic Process Metal Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Proteasomal Protein Catabolic Process Post-translational Protein Modification Regulation Of Metabolic Process Ubiquitin-protein Transferase Activity Protein Polyubiquitination Suppression Of Viral Release By Host Ubiquitin Protein Ligase Binding SUMO Transferase Activity Protein Ubiquitination Protein Catabolic Process Regulation Of Canonical NF-kappaB Signal Transduction Macromolecule Catabolic Process Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Regulation Of Protein Catabolic Process Regulation Of Gene Expression Respiratory Gaseous Exchange By Respiratory System Proteolysis Transferase Activity Regulation Of Macromolecule Biosynthetic Process Response To Stress DNA Damage Response Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Transcription By RNA Polymerase II Regulation Of Proteasomal Protein Catabolic Process Transcription Corepressor Activity Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Response To Formaldehyde Cellular Response To Vitamin B1 Regulation Of Apoptotic Process
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