GZMH and SSB

Number of citations of the paper that reports this interaction (PMID 19039329)
11

Data Source:
BioGRID (enzymatic study)

		GZMH	SSB
Gene Name		granzyme H (cathepsin G-like 2, protein h-CCPX)	Sjogren syndrome antigen B (autoantigen La)
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Membrane Intracellular Membrane-bounded Organelle	Nucleus Ribonucleoprotein Complex
	Molecular Function	Serine-type Endopeptidase Activity	TRNA Binding Nucleotide Binding MRNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Proteolysis Apoptotic Process Immune Response Protein Processing Cytolysis	TRNA Modification Histone MRNA Metabolic Process
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Peptide hormone metabolism Metabolism of Angiotensinogen to Angiotensins	RNA Polymerase III Transcription RNA Polymerase III Transcription Termination RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: SSB	9 interactors: APP CSNK2A1 CSNK2B GZMH HMGA1 IL7R NCL SPIB SPP1
Entrez ID		2999	6741
HPRD ID		00290	00168
Ensembl ID		ENSG00000100450	ENSG00000138385
Uniprot IDs		P20718	P05455
PDB IDs		1LXV 3TJU 3TJV 3TK9 4GAW	1OWX 1S79 1S7A 1YTY 1ZH5 2VOD 2VON 2VOO 2VOP
Enriched GO Terms of Interacting Partners?		Histone MRNA Metabolic Process TRNA Modification TRNA Processing RNA Modification TRNA Metabolic Process	Chemotaxis Developmental Process Response To External Stimulus Axon Guidance Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Cell Morphogenesis Cell Differentiation Positive Regulation Of Metabolic Process Interleukin-7-mediated Signaling Pathway Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Oncogene-induced Cell Senescence Synaptic Growth At Neuromuscular Junction Positive Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Locomotion Axonogenesis Anatomical Structure Morphogenesis Axon Development Regulation Of Cell Size Collateral Sprouting In Absence Of Injury Senescence-associated Heterochromatin Focus Assembly Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Growth Cell Growth Neuron Projection Morphogenesis Positive Regulation Of Cellular Senescence System Development Movement Of Cell Or Subcellular Component Positive Regulation Of Gene Expression Generation Of Neurons Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of T Cell Mediated Cytotoxicity Cell Morphogenesis Involved In Differentiation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Neurogenesis Negative Regulation Of Neuron Differentiation Negative Regulation Of Collateral Sprouting Axon Choice Point Recognition Negative Regulation Of Chromatin Silencing Negative Regulation Of Axon Regeneration Positive Regulation Of Activin Receptor Signaling Pathway Establishment Of Integrated Proviral Latency Neuron Projection Development Regulation Of Mitotic Cell Cycle Phase Transition Multicellular Organismal Development Cell Projection Morphogenesis Positive Regulation Of Cell Aging Adiponectin-activated Signaling Pathway Regulation Of Cell Cycle Phase Transition Cell Part Morphogenesis
Tagcloud ?		bc chymase chymotrypsin constitutively couldn cytotoxic elisa enzymatic estrogen existence expands granules granzyme healthy innate iranian making meanwhile nk participated possess pr premenopausal problem producing protease radioimmunoassay repertoire subsequently	advocate anticollagen asymptomatic autoantibodies autoantibody blindly cardiolipin certified dealing dsdna ganglioside gm2 harbored israeli la liabilities nc phosphatidylserine polyclonality preponderance pyruvate questioning rheumatological rheumatologist rnp silicone ssa ssdna symptomatic
Tagcloud (Difference) ?		bc chymase chymotrypsin constitutively couldn cytotoxic elisa enzymatic estrogen existence expands granules granzyme healthy innate iranian making meanwhile nk participated possess pr premenopausal problem producing protease radioimmunoassay repertoire subsequently	advocate anticollagen asymptomatic autoantibodies autoantibody blindly cardiolipin certified dealing dsdna ganglioside gm2 harbored israeli la liabilities nc phosphatidylserine polyclonality preponderance pyruvate questioning rheumatological rheumatologist rnp silicone ssa ssdna symptomatic
Tagcloud (Intersection) ?