BRF2

Description		BRF2 general transcription factor IIIB subunit
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GO Annotations	Cellular Component	Transcription Factor TFIIIB Complex Nucleus Nucleoplasm Transcription Preinitiation Complex
	Molecular Function	RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding Protein Binding Zinc Ion Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Metal Ion Binding
	Biological Process	DNA-templated Transcription Initiation Regulation Of Transcription By RNA Polymerase III Transcription By RNA Polymerase II Cellular Response To Oxidative Stress Transcription Preinitiation Complex Assembly
Pathways		RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Axial length ( 24144296)
Interacting Genes		3 interacting genes: RBL2 SNAPC4 TBP
Entrez ID		55290
HPRD ID		06115
Ensembl ID		ENSG00000104221
Uniprot IDs		Q9HAW0
PDB IDs		4ROC 4ROD 4ROE 5N9G 8ITY 8IUE 8IUH 9FSO 9FSP 9FSQ 9FSR 9FSS
Enriched GO Terms of Interacting Partners?		RNA Polymerase III General Transcription Initiation Factor Activity Transcription By RNA Polymerase III RNA Polymerase II General Transcription Initiation Factor Activity DNA Binding Regulation Of Lipid Kinase Activity SnRNA Transcription By RNA Polymerase II DNA-templated Transcription SnRNA-activating Protein Complex SnRNA Transcription By RNA Polymerase III RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding Transcription By RNA Polymerase II RNA Polymerase Transcription Factor SL1 Complex TFIIB-class Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Binding Male Pronucleus Transcription Factor TFIIA Complex Aryl Hydrocarbon Receptor Binding Pronucleus RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Preinitiation Complex Assembly Female Pronucleus Female Germ Cell Nucleus SnRNA Transcription Core Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding Transcription Factor TFIID Complex Nucleobase-containing Compound Biosynthetic Process MRNA Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter SnRNA Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Preinitiation Complex Assembly Male Germ Cell Nucleus Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Chromatin MRNA Transcription Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Euchromatin Nucleoplasm Promoter-specific Chromatin Binding Negative Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Initiation
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