POLR3E and POLR3D

Number of citations of the paper that reports this interaction (PMID 12391170)
22

Data Source:
HPRD (in vivo)

		POLR3E	POLR3D
Gene Name		polymerase (RNA) III (DNA directed) polypeptide E (80kD)	polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm DNA-directed RNA Polymerase III Complex Centrosome Cytosol	Nuclear Chromatin Nucleoplasm DNA-directed RNA Polymerase III Complex Cytoplasm Cytosol
	Molecular Function	RNA Polymerase III Activity	RNA Polymerase III Activity DNA Binding Chromatin Binding
	Biological Process	Transcription From RNA Polymerase III Promoter Transcription Elongation From RNA Polymerase III Promoter Termination Of RNA Polymerase III Transcription Gene Expression Positive Regulation Of Type I Interferon Production Innate Immune Response Defense Response To Virus	Transcription From RNA Polymerase III Promoter Transcription Elongation From RNA Polymerase III Promoter Termination Of RNA Polymerase III Transcription Gene Expression Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus
Pathways		RNA Polymerase III Transcription Termination RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Initiation From Type 2 Promoter Innate Immune System	RNA Polymerase III Transcription Termination RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Initiation From Type 2 Promoter Innate Immune System
Drugs
Diseases
GWAS			Hypertriglyceridemia ( 23505323)
Protein-Protein Interactions		2 interactors: POLR3A POLR3D	13 interactors: APEX1 ATF3 HNRNPAB HOXA10 HOXC9 MAPK11 MSX2 NR2E3 POLR3E RBFOX2 RHOXF2 TAB1 ZNF496
Entrez ID		55718	661
HPRD ID		15155	01755
Ensembl ID		ENSG00000058600	ENSG00000168495
Uniprot IDs		Q9NVU0	P05423
PDB IDs
Enriched GO Terms of Interacting Partners?		Termination Of RNA Polymerase III Transcription Transcription Elongation From RNA Polymerase III Promoter Positive Regulation Of Interferon-beta Production Regulation Of Interferon-beta Production Transcription From RNA Polymerase III Promoter DNA-templated Transcription, Termination Positive Regulation Of Type I Interferon Production DNA-templated Transcription, Elongation Regulation Of Type I Interferon Production Defense Response To Virus Response To Virus Positive Regulation Of Cytokine Production Regulation Of Cytokine Production Response To Other Organism Response To Biotic Stimulus Innate Immune Response Immune Response Defense Response Response To External Stimulus Immune System Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Innate Immune Response RNA Metabolic Process Regulation Of Innate Immune Response Response To Stress Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Organ Development Developmental Process Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Anatomical Structure Morphogenesis Positive Regulation Of Metabolic Process Intracellular Receptor Signaling Pathway Biosynthetic Process Anatomical Structure Development Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Anterior/posterior Pattern Specification Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Epithelial To Mesenchymal Transition Positive Regulation Of Transcription, DNA-templated Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway System Development Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tagcloud ?			address ago1 antisense argonaute cis cytoplasm directed directs encoded existence h3k27me3 interference micrornas mir mirna mirnas orientation pcg polycomb posttranscriptional proximal rnai searched silence silencing start tgs transcriptionally tri
Tagcloud (Difference) ?			address ago1 antisense argonaute cis cytoplasm directed directs encoded existence h3k27me3 interference micrornas mir mirna mirnas orientation pcg polycomb posttranscriptional proximal rnai searched silence silencing start tgs transcriptionally tri
Tagcloud (Intersection) ?