RASL11B and GEMIN6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RASL11B	GEMIN6
Description		RAS like family 11 member B	gem nuclear organelle associated protein 6
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Transforming Growth Factor Beta Receptor Binding Protein Binding GTP Binding Hydrolase Activity	RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways			snRNP Assembly SARS-CoV-2 modulates host translation machinery
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Metabolite levels ( 23823483) Moderate or severe prolonged lymphopenia in dimethyl fumarate-treated relapsing-remitting multiple sclerosis ( 31749835) Response to citalopram or escitalopram and depression ( 27622933) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		9 interacting genes: APP EWSR1 GEMIN6 LNX1 LRRK2 MAGI1 MFHAS1 NEDD4 NEDD4L	16 interacting genes: ACOT11 DDIT4L GEMIN7 NUFIP1 RASL11B RN7SL1 RNU1-1 RNU2-1 SNRPB SNRPD2 SNRPD3 SNRPE SNRPF SNRPG STRAP TOX4
Entrez ID		65997	79833
HPRD ID		15216	06110
Ensembl ID		ENSG00000128045	ENSG00000152147
Uniprot IDs		Q9BPW5	Q8WXD5
PDB IDs			1Y96 7BBL
Enriched GO Terms of Interacting Partners?		Synapse Organization Neuromuscular Junction Development Cell Junction Organization Positive Regulation Of Protein Catabolic Process Negative Regulation Of Potassium Ion Export Across Plasma Membrane Sodium Channel Inhibitor Activity Regulation Of Synapse Organization Cellular Response To Manganese Ion Potassium Channel Inhibitor Activity Regulation Of Potassium Ion Export Across Plasma Membrane Response To Manganese Ion Negative Regulation Of Sodium Ion Transport Regulation Of Protein Catabolic Process Golgi-associated Vesicle Regulation Of Membrane Potential Cellular Response To Catecholamine Stimulus Response To Catecholamine Transmembrane Transporter Binding Receptor Catabolic Process Endocytosis Negative Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Endocytosis Negative Regulation Of Potassium Ion Transport Positive Regulation Of Catabolic Process Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Protein Localization Regulation Of Toll-like Receptor Signaling Pathway Import Into Cell Postsynapse Regulation Of Plasma Membrane Bounded Cell Projection Organization Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Cell Projection Organization Regulation Of CAMP/PKA Signal Transduction Ubiquitin-protein Transferase Activity Receptor Metabolic Process Negative Regulation Of Protein Localization To Nucleus Modulation Of Excitatory Postsynaptic Potential Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Membrane Depolarization Cytoplasm Protein Monoubiquitination Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Macrophage Activation Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Protein Metabolic Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway	SMN-Sm Protein Complex 7-methylguanosine Cap Hypermethylation Spliceosomal SnRNP Assembly U2 SnRNP U4 SnRNP Methylosome Protein-RNA Complex Assembly Small Nuclear Ribonucleoprotein Complex U1 SnRNP U7 SnRNP U5 SnRNP U2-type Prespliceosome Assembly U12-type Spliceosomal Complex U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome U4/U6 X U5 Tri-snRNP Complex Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome U2-type Precatalytic Spliceosome RNA Splicing, Via Transesterification Reactions PICln-Sm Protein Complex RNA Methylation Catalytic Step 2 Spliceosome RNA Splicing Macromolecule Methylation Protein-containing Complex Assembly MRNA Processing Precatalytic Spliceosome Protein-containing Complex Organization RNA Modification Spliceosomal Complex RNA Processing Methylation MRNA Metabolic Process Ribonucleoprotein Complex U2 SnRNP Binding Cellular Component Assembly Telomerase Holoenzyme Complex RNA Metabolic Process RNA Binding Histone Pre-mRNA DCP Binding Spliceosomal Tri-snRNP Complex Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process SMN Complex U2-type Prespliceosome Telomerase RNA Binding Protein Methylation Pre-mRNA Branch Point Binding MRNA Branch Site Recognition
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