NME1-NME2 and NME4

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		NME1-NME2	NME4
Gene Name		NME1-NME2 readthrough	NME/NM23 nucleoside diphosphate kinase 4
Image
Gene Ontology Annotations	Cellular Component		Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Cytosol
	Molecular Function		Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Protein Complex Binding Metal Ion Binding
	Biological Process		Purine Nucleotide Metabolic Process Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process Pyrimidine Nucleotide Metabolic Process UTP Biosynthetic Process CTP Biosynthetic Process Nucleoside Metabolic Process Nucleoside Triphosphate Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Regulation Of Apoptotic Process Small Molecule Metabolic Process Nucleobase-containing Small Molecule Metabolic Process
Pathways		Metabolism of nucleotides Synthesis and interconversion of nucleotide di- and triphosphates	Metabolism of nucleotides Synthesis and interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS			Red blood cell traits ( 23446634)
Protein-Protein Interactions		2 interactors: NME2 NME4	7 interactors: LSM8 NME1 NME1-NME2 NME2 SOCS3 SUV39H2 TRIP13
Entrez ID		654364	4833
HPRD ID			03489
Ensembl ID		ENSG00000243678	ENSG00000103202
Uniprot IDs		P22392	A2IDD0 O00746
PDB IDs		1NSK 1NUE 3BBB 3BBC 3BBF	1EHW
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Small Molecule Interconversion GTP Biosynthetic Process UTP Biosynthetic Process GTP Metabolic Process UTP Metabolic Process CTP Biosynthetic Process Nucleoside Diphosphate Phosphorylation Pyrimidine Ribonucleotide Biosynthetic Process Pyrimidine Nucleoside Biosynthetic Process Pyrimidine Nucleotide Biosynthetic Process Nucleotide Phosphorylation Nucleoside Diphosphate Metabolic Process Pyrimidine Nucleoside Metabolic Process Pyrimidine Nucleotide Metabolic Process Nucleoside Triphosphate Biosynthetic Process Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Purine Nucleoside Metabolic Process Ribonucleotide Metabolic Process Nucleoside Metabolic Process Nucleotide Biosynthetic Process Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Nucleotide Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Peptidyl-histidine Phosphorylation Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of Epidermal Cell Differentiation Organophosphate Metabolic Process Regulation Of Keratinocyte Differentiation Positive Regulation Of Epidermis Development Response To Testosterone Regulation Of Epidermal Cell Differentiation Cellular Response To Fatty Acid Regulation Of Apoptotic Process Response To Amine Negative Regulation Of Myeloid Leukocyte Differentiation Regulation Of Cell Death Cellular Response To Drug Cellular Response To Glucose Stimulus Regulation Of Epidermis Development Response To Fatty Acid Hippocampus Development Positive Regulation Of Epithelial Cell Differentiation Phosphorylation Cellular Glucose Homeostasis Cellular Response To Carbohydrate Stimulus Negative Regulation Of Myeloid Cell Differentiation Limbic System Development Regulation Of Myeloid Leukocyte Differentiation	GTP Biosynthetic Process UTP Biosynthetic Process GTP Metabolic Process UTP Metabolic Process CTP Biosynthetic Process Nucleoside Diphosphate Phosphorylation Pyrimidine Ribonucleotide Biosynthetic Process Pyrimidine Nucleoside Biosynthetic Process Pyrimidine Nucleotide Biosynthetic Process Nucleotide Phosphorylation Nucleoside Diphosphate Metabolic Process Pyrimidine Nucleoside Metabolic Process Pyrimidine Nucleotide Metabolic Process Nucleoside Triphosphate Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Purine Nucleoside Metabolic Process Response To Testosterone Cell Differentiation Ribonucleotide Metabolic Process Nucleoside Metabolic Process Nucleotide Biosynthetic Process Purine Nucleotide Metabolic Process Cellular Response To Fatty Acid Ribose Phosphate Metabolic Process Response To Amine Negative Regulation Of Myeloid Leukocyte Differentiation Cellular Response To Drug Male Meiosis Cellular Response To Glucose Stimulus Response To Fatty Acid Hippocampus Development Cellular Glucose Homeostasis Cellular Response To Carbohydrate Stimulus Negative Regulation Of Myeloid Cell Differentiation Nucleobase-containing Compound Metabolic Process Limbic System Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleotide Metabolic Process Regulation Of Myeloid Leukocyte Differentiation Cellular Nitrogen Compound Metabolic Process Response To CAMP Response To Glucose Nucleobase-containing Small Molecule Metabolic Process Response To Organophosphorus Positive Regulation Of Epithelial Cell Proliferation Developmental Process Nitrogen Compound Metabolic Process
Tagcloud ?			5q aml analysed array arrays blast cdna cluster comprising de differently ercc1 flt1 larger myelodysplastic novo pcna probes profiles progressive qrt raeb rcmd represents subtypes transformation unfavorable validated whose
Tagcloud (Difference) ?			5q aml analysed array arrays blast cdna cluster comprising de differently ercc1 flt1 larger myelodysplastic novo pcna probes profiles progressive qrt raeb rcmd represents subtypes transformation unfavorable validated whose
Tagcloud (Intersection) ?