OCM and CKMT1B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		OCM	CKMT1B
Description		oncomodulin	creatine kinase, mitochondrial 1B
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GO Annotations	Cellular Component	Cytoplasm	Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Metal Ion Binding	Nucleotide Binding Catalytic Activity Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Transferase Activity, Transferring Phosphorus-containing Groups
	Biological Process		Phosphocreatine Biosynthetic Process
Pathways			Creatine metabolism
Drugs			Creatine Phosphocreatine
Diseases
GWAS
Interacting Genes		3 interacting genes: CKMT1A CKMT1B SDCBP	12 interacting genes: ASB9 CALM1 CTNNA3 HPCA NUTF2 OCM PPP1R16A PSMC3 RXRG SFRP4 SLC25A5 VDAC1
Entrez ID		654231	1159
HPRD ID		19267	00424
Ensembl ID		ENSG00000122543	ENSG00000237289
Uniprot IDs		P0CE72	P12532
PDB IDs		1TTX	1QK1 9B04 9B05 9B0T 9B0U 9B14 9B16
Enriched GO Terms of Interacting Partners?		Phosphocreatine Biosynthetic Process Creatine Kinase Activity Transferase Activity, Transferring Phosphorus-containing Groups Interleukin-5 Receptor Complex Modified Amino Acid Metabolic Process Interleukin-5 Receptor Binding Positive Regulation Of Extracellular Exosome Assembly Syndecan Binding Catalytic Activity Regulation Of Extracellular Exosome Assembly Substrate-dependent Cell Migration, Cell Extension Mitochondrial Inner Membrane Organophosphate Biosynthetic Process Negative Regulation Of Receptor Internalization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Kinase Activity Cytoskeletal Anchor Activity Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Receptor-mediated Endocytosis Frizzled Binding	Mitochondrial Permeability Transition Pore Complex Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Mitophagy Positive Regulation Of Autophagy Of Mitochondrion Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Autophagy Of Mitochondrion Positive Regulation Of Catabolic Process Mitochondrial Nucleoid Regulation Of Mitophagy Negative Regulation Of Calcium Ion Transport Negative Regulation Of Calcium Ion Transmembrane Transport Regulation Of Action Potential Regulation Of Monoatomic Cation Transmembrane Transport Negative Regulation Of Sodium-dependent Phosphate Transport Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Transmembrane Transporter Activity Negative Regulation Of Cation Transmembrane Transport Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cardiac Muscle Contraction Negative Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transporter Activity Regulation Of Receptor Internalization Response To Ketamine Adenine Nucleotide Transmembrane Transporter Activity Mitochondrial ADP Transmembrane Transport ATP:ADP Antiporter Activity MMXD Complex Positive Regulation Of Macroautophagy Regulation Of Transport Adenine Transmembrane Transporter Activity Oxidative Phosphorylation Uncoupler Activity Adenine Transport Transmembrane Transporter Binding Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Transport Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Response To Calcium Ion Negative Regulation Of Monoatomic Ion Transport Regulation Of Heart Rate Negative Regulation Of Transmembrane Transport Regulation Of Monoatomic Ion Transport Regulation Of Striated Muscle Contraction Response To Aroclor 1254 Regulation Of Receptor-mediated Endocytosis Dendritic Spine Head
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