ZG16 and PUF60

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZG16	PUF60
Description		zymogen granule protein 16	poly(U) binding splicing factor 60
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Apparatus Golgi Lumen Cytoplasmic Vesicle Zymogen Granule Membrane Mucus Layer	Nucleus Nucleoplasm Cell Junction Ribonucleoprotein Complex
	Molecular Function	Protein Binding Carbohydrate Binding Peptidoglycan Binding	Nucleic Acid Binding DNA Binding RNA Binding Protein Binding Identical Protein Binding Cadherin Binding
	Biological Process	Protein Transport Defense Response To Gram-positive Bacterium Suppression Of Symbiont Entry Into Host	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splice Site Recognition MRNA Processing Apoptotic Process RNA Splicing
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Interacting Genes		11 interacting genes: ASPH CTNNA3 GLYCTK KCNIP3 PUF60 SGTA SGTB UBE2I UBQLN1 UBQLN2 UBQLN4	109 interacting genes: ARL8A BORCS5 CACNA1A CCNC CD101 CEBPA CHD3 CPEB2 DDIT4L DDX50 ERG ERP29 FBXO7 FHL2 FTHL17 FUBP1 H1-2 ID3 IQCN KHDC4 MED28 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR9-1 MIR9-3 MIR92A1 MIR92A2 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F2 MIRLET7G MIRLET7I MREG MYCBP2 OGT PCBP1 PCBP3 PPP1R16A PTBP2 QRICH1 RAD23B RAP1GDS1 SAP30BP SDCBP SF1 SIAH1 SNRPA SNRPF SRSF11 SUGP1 TAF2 TH U2AF2 UBE2I UBTFL1 UPF2 VIM YWHAG ZG16
Entrez ID		653808	22827
HPRD ID			18051
Ensembl ID		ENSG00000174992	ENSG00000179950
Uniprot IDs		O60844	E9PL19 E9PQ56 H0YEM1 Q9UHX1
PDB IDs		3APA 3VY6 3VY7 3VZE 3VZF 3VZG 7O3I 7O4P 7O88	2DNY 2KXF 2KXH 2QFJ 3DXB 3UE2 3US5 3UWT 5KVY 5KW1 5KW6 5KWQ 6LUR 6SLO 7Q8A 7Z3X
Enriched GO Terms of Interacting Partners?		TRC Complex Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Regulation Of Proteolysis Positive Regulation Of Response To Endoplasmic Reticulum Stress Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Autophagosome Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of Macroautophagy Macromolecule Catabolic Process Regulation Of Cellular Response To Stress Positive Regulation Of Protein Catabolic Process Identical Protein Binding Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Response To Endoplasmic Reticulum Stress Proteolysis Regulation Of Monoatomic Cation Transmembrane Transport Catabolic Process SUMO Conjugating Enzyme Activity Negative Regulation Of Store-operated Calcium Channel Activity Glycerate Kinase Activity Regulation Of Monoatomic Ion Transmembrane Transport Autophagy Protein Targeting To Membrane Positive Regulation Of Protein Metabolic Process Peptidyl-aspartic Acid 3-dioxygenase Activity Regulation Of Transmembrane Transporter Activity Regulation Of Cardiac Muscle Contraction Regulation Of Metal Ion Transport Regulation Of Monoatomic Ion Transmembrane Transporter Activity Negative Regulation Of G Protein-coupled Receptor Internalization Nuclear Proteasome Complex Regulation Of Autophagy Regulation Of Protein Metabolic Process Autophagosome Assembly Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Regulation Of Striated Muscle Contraction RING-like Zinc Finger Domain Binding Autophagosome Organization	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Extracellular Vesicle MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Angiogenesis MRNA Destabilization Negative Regulation Of Vasculature Development RNA Destabilization Regulation Of Metabolic Process Regulation Of Angiogenesis Negative Regulation Of Cell Migration Regulation Of Vasculature Development Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Translation Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Protein Metabolic Process Negative Regulation Of Cytokine Production Negative Regulation Of Developmental Process Regulation Of MRNA Stability Regulation Of RNA Stability Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Multicellular Organismal Process Regulation Of MRNA Metabolic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Endothelial Cell Migration Regulation Of Endothelial Cell Migration Regulation Of Locomotion Extracellular Space Regulation Of Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Cell Motility
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